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ProteomicsThe cardiac syndecan-4 interactome:A role for syndecan-4 innuclear translocation of muscle LIM protein (MLP)
Biomechanical stimuli and extracellular matrix cues are important initiators for the cardiac remodeling process, and signaling hubs in the sarcolemma are important contact points between the extracellular space and cell interior, sensing and transducing biomechanical signals into a cellular response...
ORGANISM(S): Rattus norvegicus (Rat) 
2019-04-09 | PXD011249 | Pride
Hypertrophy Heart Csrp3 Syndecan-4 Interactome Mlp Nuclear translocation Biomechanical stress 
ProteomicsSyndecan-4 is a maestro of gastric cancer cell invasion and communication that underscores poor survival
Gastric cancer is a dominating cause of cancer-associated mortality with limited therapeutic options. Here, we show that syndecan-4 (SDC4), a plasma membrane proteoglycan, is highly expressed in intestinal subtype gastric tumours and that this signature associates with patients’ poor survival. Furth...
ORGANISM(S): Homo sapiens (Human) 
2023-05-05 | PXD035679 | Pride
Extracellular vesicles Extracellular communication Gastric cancer Syndecan-4 Heparan sulfate proteoglycans Cancer cell invasion 
UnknownThe cardiac syndecan-4 interactome reveals a role for syndecan-4 in nuclear translocation of muscle LIM protein (MLP).
Not available
S-EPMC6552415 | biostudies-literature
UnknownCleavage of syndecan-4 by ADAMTS1 provokes defects in adhesion.
Not available
S-EPMC3807939 | biostudies-literature
UnknownSyndecan-1 downregulates syndecan-4 expression by suppressing the ERK1/2 and p38 MAPK signaling pathways in cultured vascular endothelial cells.
Not available
S-EPMC8099740 | biostudies-literature
UnknownHeparan sulfate chain valency controls syndecan-4 function in cell adhesion.
Not available
S-EPMC2863221 | biostudies-literature
UnknownSyndecan-4/PAR-3 signaling regulates focal adhesion dynamics in mesenchymal cells.
Not available
S-EPMC7433185 | biostudies-literature
UnknownThe expression of syndecan-1, syndecan-4 and decorin in healthy human breast tissue during the menstrual cycle.
Not available
S-EPMC2864278 | biostudies-literature
UnknownSyndecan-4 phosphorylation is a control point for integrin recycling.
Not available
S-EPMC3605578 | biostudies-literature
UnknownSyndecan-4 tunes cell mechanics by activating the kindlin-integrin-RhoA pathway.
Not available
S-EPMC7260055 | biostudies-literature
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