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GenomicsEffect of Cardiac LIM Protein (CSRP3) on human proximal tubule epithelial cells
Effect of Cardiac LIM Protein (CSRP3) on human proximal tubule epithelial cells
PRJNA1156043 | ENA
TranscriptomicsEffect of Cardiac LIM Protein (CSRP3) on human proximal tubule epithelial cells
Cardiac LIM protein (CSRP3) is released from the heart after cardiac injury and transits the plasma to the renal filtrate. CSRP3 has a well described transcriptionally-active role in myocardiocyte development and response to stress. Although it appears in endocytic vesicles within tubular epithelial...
ORGANISM(S): Homo sapiens 
2025-08-20 | GSE276233 | GEO
TranscriptomicsCysteine and Glycine Rich Protein 3 (Csrp3) modulates cardiomyocyte mitotic cell cycle entry through Ring Finger Protein 5 (Rnf5)/p38 MAPK dependent pathway
Adult cardiomyocyte (CM) has limited proliferative capacity, which is correlated with rigid sarcomere structures. Our previous studies showed that overexpression of Cdk1, Cdk4, Ccnb, and Ccnd (collectively 4F) induces adult CM proliferation with observed sarcomere disassembly during mitosis. However...
ORGANISM(S): Mus musculus 
2026-08-05 | GSE342169 | GEO
GenomicsCysteine and Glycine Rich Protein 3 (Csrp3) modulates cardiomyocyte mitotic cell cycle entry through Ring Finger Protein 5 (Rnf5)/p38 MAPK dependent pathway
Cysteine and Glycine Rich Protein 3 (Csrp3) modulates cardiomyocyte mitotic cell cycle entry through Ring Finger Protein 5 (Rnf5)/p38 MAPK dependent pathway
PRJNA1505726 | ENA
UnknownCoding sequence mutations identified in MYH7, TNNT2, SCN5A, CSRP3, LBD3, and TCAP from 313 patients with familial or idiopathic dilated cardiomyopathy.
Not available
S-EPMC2633921 | biostudies-literature
TranscriptomicsSpatiotemporal transcriptome analysis reveals critical roles for mechano-sensing genes at the border zone in remodeling after myocardial infarction
The underlying mechanisms of ventricular remodeling after myocardial infarction (MI) remain largely unknown. Here, we performed an integrative analysis of spatial transcriptomics and single-nucleus RNA-seq in a murine MI model and found that mechanical stress-response genes are expressed at the bord...
ORGANISM(S): Mus musculus 
2022-07-25 | GSE176092 | GEO
UnknownMuscle LIM protein/CSRP3: a mechanosensor with a role in autophagy.
Not available
S-EPMC4981024 | biostudies-literature
ProteomicsPabpn1-driven cytoskeletal rearrangement induces muscle wasting
Poly(A) binding protein nuclear 1 (PABPN1) is a multifunctional regulator of mRNA processing. PABPN1 inhibits alternative polyadenylation (APA), and in conditions with reduced PABPN1 levels APA utilization causes genome-wide mRNA dysregulation. PABPN1 levels decline from midlife onwards in Oculophar...
ORGANISM(S): Mus musculus (Mouse) 
2020-07-06 | PXD004865 | Pride
Pfn1 Pabpn1 Mouse Csrp3 Progenesis Lfq Murc 
UnknownA novel gene-trap line reveals the dynamic patterns and essential roles of cysteine and glycine-rich protein 3 in zebrafish heart development and regeneration.
Not available
S-EPMC10982097 | biostudies-literature
UnknownCysteine- and glycine-rich protein 3 regulates glucose homeostasis in skeletal muscle.
Not available
S-EPMC6139493 | biostudies-literature
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