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TranscriptomicsTranscription profiling of four mouse bone marrow hematopoietic stem cells (HSC) early B lineage stages(MLP, CLP, Fr.A, Fr.B) to identify coordinately regulated gene as cells progress down the B cell development pathway
Differentiation from hematopoietic stem cells (HSC) to early B-lineage cells proceeds through a series of intermediate stages, during which cells are thought to become progressively more restricted in their developmental potential. RNAs were prepared from four early B lineage stages(MLP, CLP, Fr.A, ...
ORGANISM(S): Mus musculus 
2006-12-16 | E-MEXP-559 | biostudies-arrayexpress
ProteomicsThe cardiac syndecan-4 interactome:A role for syndecan-4 innuclear translocation of muscle LIM protein (MLP)
Biomechanical stimuli and extracellular matrix cues are important initiators for the cardiac remodeling process, and signaling hubs in the sarcolemma are important contact points between the extracellular space and cell interior, sensing and transducing biomechanical signals into a cellular response...
ORGANISM(S): Rattus norvegicus (Rat) 
2019-04-09 | PXD011249 | Pride
Hypertrophy Heart Csrp3 Syndecan-4 Interactome Mlp Nuclear translocation Biomechanical stress 
TranscriptomicsTime-course analysis of transcriptomes of human long-term (LT) and short-term (ST) hematopoietic stem cells (HSC) after xenotransplantation
Here we tracked transcriptional changes in LT, ST-HSC and MLP after transplantation into immunocompromised mice. We show that LT- and ST-HSC activate similar pathways upon transplantation but they modulate distinct sets of genes. Total RNA was obtained from flow-sorted populations of human LT-, ST-H...
ORGANISM(S): Homo sapiens 
2015-02-20 | E-GEOD-58299 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of muscles from mice subjected to a single bout of eccentric contractions to understand the molecular mechanism of eccentric contraction-induced injury.
Mice were subjected to 50 eccentric contractions (EC) or 50 isometric contractions (IC) using a non-invasive model, and then sacrificed 48 hours later. RNA from the tibialis anterior of 4 animals were pooled and then split into two groups for hybridization onto two separate Affymetrix MGU74Av2 chips...
ORGANISM(S): Mus musculus 
2007-11-06 | E-GEOD-435 | biostudies-arrayexpress
GenomicsGenetic and Environmental Determinants of Multicellular-like Phenotype Formation in Fission Yeast
MLP formation in S. pombe
PRJEB69522 | ENA
GenomicsMLP promotes Axon Regeneration
Muscle LIM Protein is a Regeneration Associated Protein and promotes Axon Regeneration
PRJEB29357 | ENA
TranscriptomicsSingle Cell RNA sequencing analysis of human haemopoietic lympho-myeloid progenitor populations (LMPP, MLP and GMP)
We performed single cell RNA sequencing of human haemopoietic lympho-myeloid progenitors with the aim to separate functionally and transcriptionally distinct progenitors within the heterogeneous GMP, LMPP and MLP populations. We performed RNA sequencing in a total of 415 single cells. From donors 1 ...
ORGANISM(S): Homo sapiens 
2017-11-11 | GSE100618 | GEO
TranscriptomicsNuclear pore complex evolution: A trypanosome Mlp analog functions in chromosomal segregation but lacks transcriptional barrier activity
The nuclear pore complex (NPC) has dual roles in nucleocytoplasmic transport and chromatin organisation. In many eukaryotes the coiled coil Mlp/Tpr proteins of the NPC nuclear basket have specific roles in interactions with chromatin and defining specialised regions of active transcription, while Ml...
ORGANISM(S): Trypanosoma brucei 
2014-04-03 | GSE56436 | GEO
TranscriptomicsNuclear pore complex evolution: A trypanosome Mlp analog functions in chromosomal segregation but lacks transcriptional barrier activity
The nuclear pore complex (NPC) has dual roles in nucleocytoplasmic transport and chromatin organisation. In many eukaryotes the coiled coil Mlp/Tpr proteins of the NPC nuclear basket have specific roles in interactions with chromatin and defining specialised regions of active transcription, while Ml...
ORGANISM(S): Trypanosoma brucei 
2014-04-03 | E-GEOD-56436 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of four yeast strains grown in SC medium and shifted for 2.5h to 37C: YRA1 wild type, YRA1 mlp2916; GFP-yra1-8, and GFP-yra1-8 mlp2916
Comparison of mRNA levels in four yeast strains grown in SC medium and shifted for 2.5h to 37C: YRA1 wild-type, YRA1 mlp2Δ GFP-yra1-8, and GFP-yra1-8 mlp2Δ
ORGANISM(S): Saccharomyces cerevisiae 
2004-12-31 | E-MEXP-130 | biostudies-arrayexpress
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