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ProteomicsFUT3-associated proteomic profiling in T3M4 pancreatic cancer cells following FUT3 knockdown
This dataset contains co-immunoprecipitation-based quantitative proteomic data generated from T3M4 pancreatic cancer cells following FUT3 knockdown. FUT3-associated protein complexes were enriched by co-immunoprecipitation and subsequently analyzed by TMT-based LC-MS/MS. The aim of this experiment w...
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD083797 | Pride
T3m4 Proteomics Co-immunoprecipitation Tmt Pancreatic ductal adenocarcinoma Fut3 Ddx21 Lc-ms/ms 
UnknownACAGT-007a, an ERK MAPK Signaling Modulator, in Combination with AKT Signaling Inhibition Induces Apoptosis in KRAS Mutant Pancreatic Cancer T3M4 and MIA-Pa-Ca-2 Cells.
Not available
S-EPMC8869916 | biostudies-literature
TranscriptomicsExpression data from pancreatic stellate cells
tumor-stroma crosstalk drives pancreatic carcinogenesis we used time-resolved genome-wide transcriptional profiling to analyse changes caused by co-exposure of pancreatic tumor and stellate cells Primary pancreatic Stellate cells (PSC) were treated with a cumulative supernatant of pancreatic tumor ...
ORGANISM(S): Homo sapiens 
2013-08-09 | E-GEOD-49583 | biostudies-arrayexpress
TranscriptomicsRetrotransposons and the global shutdown of homeostatic innate immunity in the tumor cells by oncolytic parvovirus H-1PV
RNAseq-based comparison of H-1PV infected vs. non-infected cells revealed global suppression of antiviral innate immunity in the PDAC cells (AsPC1, MiaPaca2 and T3M4 taken at 48hpi) and global stimulation – in the healthy donor PBMCs (taken at 24hpi).
ORGANISM(S): Homo sapiens 
2020-10-29 | GSE160322 | GEO
TranscriptomicsExperimental gene expression analysis of 12 cancer cell lines
The accurate choice of anti-cancer drugs is important problem of modern medicine. We developed a new method for the selection of targeted drugs based on detection of specific intracellular signaling and metabolic pathways in the bioinformatic system termed OncoFinder before the treatment. We obtaine...
ORGANISM(S): Homo sapiens 
2015-01-27 | E-GEOD-65314 | biostudies-arrayexpress
UnknownConcomitant targeting of EGF receptor, TGF-beta and SRC points to a novel therapeutic approach in pancreatic cancer.
Not available
S-EPMC3384603 | biostudies-literature
ProteomicsExosomes and cells protein content from human subpopulations of pancreatic ductal adenocarcinoma (PDAC)
Characterization of the protein composition of exosomes and subpopulations of cells from four human PDAC cell lines (BxPC-3, PANC-1, T3M4, and MIA PaCa-2), via liquid chromatography electrospray ionization tandem mass spectrometry (LC/ESI–MS/MS).
ORGANISM(S): Homo sapiens (Human) 
2022-01-25 | PXD023529 | Pride
Cancer Exosomes Pancreas Pdac 
TranscriptomicsA single-cell proteomic and transcriptomic assay identifies genes related to polyfunctionality of CAR-T cells targeting GPC1 in pancreatic cancer
To understand the molecular determinants of CAR-T cell polyfunctionality, we simultaneously measured the protein and RNA expression levels of 23 single CD8+ D4-IgG4H-CD28TM CAR T cells targeting GPC1 stimulated with T3M4 pancreatic cancer cells. We identified two CAR-T clusters, low polyfunctionalit...
ORGANISM(S): Homo sapiens 
2023-03-04 | GSE220536 | GEO
UnknownDeltaNp63alpha-mediated induction of epidermal growth factor receptor promotes pancreatic cancer cell growth and chemoresistance.
Not available
S-EPMC3203907 | biostudies-literature
UnknownStarvation mediates pancreatic cancer cell sensitivity to ferroptosis via ERK1/2, JNK and changes in the cell mesenchymal state.
Not available
S-EPMC9106375 | biostudies-literature
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