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ProteomicsQuantitative Histone Acetylation
This work details a previously uncharacterized cross-talk between the Gcn5 bromodomain "reader" function and enzymatic HAT activity that may ultimately affect gene expression.
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2014-08-14 | PXD001167 | Pride
Transcription coactivators Histone modification Histone acetylation Epigentics Bromodomain 
ProteomicsYLR455 affinity purification - An H3K36me3 binding PWWP protein targets the NuA3 acetyltransferase complex to coordinate transcriptional elongation at coding regions
These studies define a new form of the NuA3 complex that associates with H3K36me3 to effect transcriptional elongation.
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2014-08-14 | PXD001156 | Pride
Epigenetics Pwwp domain Histone methylation Gene regulation Nua3 Transcription elongation Histone acetylation 
ProteomicsQuantitative analysis of the exoproteome from a Staphylococcus aureus LAC sarA mutant
The staphylococcal accessory regulator A (sarA) impacts the extracellular accumulation of Staphylococcus aureus virulence factors at the level of intracellular production and extracellular protease-mediated degradation. To assess the relative impact of these two functions, we previously used a prote...
ORGANISM(S): Staphylococcus aureus 
2018-11-21 | PXD009614 | Pride
Protease Sara Staphylococcus aureus Proteolysis Gelcms 
ProteomicsProteomic Analysis of an Arsenic Response Locus
Arsenic exposure is a global health problem. Millions of people encounter arsenic through contaminated drinking water, consumption, and inhalation. The arsenic response locus in budding yeast is responsible for the detoxification of arsenic and its removal from the cell. This locus constitutes a con...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2020-05-07 | PXD009902 | Pride
Arsenic Yeast Chap-ms Crispr 
ProteomicsQuantitative histone mass spectrometry identifies elevated histone H3 lysine 27 trimethylation in melanoma
Normal cell growth is characterized by a regulated epigenetic program that drives cellular activities such as gene transcription, DNA replication and DNA damage repair. Perturbation of this epigenetic program can lead to events such as mis-regulation of gene transcription and diseases such as cancer...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-22 | MSV000079979 | MassIVE
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