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Proteome profiles of isolated peripheral human neutrophils pretreated with purified Tamm-Horsfall protein and stimulated to undergo NETosis with PMA.
ORGANISM(S): Homo sapiens (Human) 
2024-09-23 | PXD045468 | Pride
Single cell RNASeq of murine bone marrow derived macrophages (BMDM) treated with non-polymerizing Tamm-Horsfall Protein
To elucidate changes in macrophage subpopulations in the presence of non-polymerizing Tamm-Horsfall Protein, we performed single cell RNAseq on mouse bone marrow derived macrophages following 18 hour treatment with either a non-polymerizing form of Tamm-Horsfall Protein or vehicle. After treatment, ...
ORGANISM(S): Mus musculus 
2022-06-23 | GSE189433 | GEO
Single cell RNASeq of whole mouse kidneys from Uromodulin/Tamm horsfall protein knock-out mice
We identified an alternatively spliced UMOD which is uniquely localized intracellularly. This intracellular isoform enhanced mitochondrial function. To understand its molecular mechanism, we performed affinity-purification coupled to mass spectrometry using MDCK cell lysate expressing UMOD variant. ...
ORGANISM(S): Canis Lupus Familiaris (ncbitaxon:9615) Homo Sapiens (ncbitaxon:9606) 
2024-03-15 | MSV000094329 | MassIVE
Urinary extracellular vesicles (uEV) are a precious new source of biomarkers reflecting the physiological state of the upstream parent cells and organ systems. However, urinary Tamm-Horsfall Protein (THP; uromodulin) interferes heavily with all vesicle isolation attempts, precipitates with normal ur...
ORGANISM(S): Homo sapiens (Human) 
2019-09-30 | PXD013429 | Pride
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