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Isobaric tagging is a method of choice in Mass Spectrometry (MS)-based proteomics for comparing multiple conditions at a time. Despite its multiplexing capabilities, when multiple experiments are merged for comparison in large sample-size studies, some drawbacks appears, due to the presence of missi...
ORGANISM(S): Homo sapiens (Human) 
2018-05-01 | PXD008029 | Pride
Stable isotope labeling of peptides is the basis for numerous mass spectrometry-based quantification strategies. Isobaric tagging and metabolic labeling, namely TMT and SILAC, are among the most widely used techniques for relative protein quantification. Here we report an alternative, precursor-base...
ORGANISM(S): Homo sapiens (Human) 
2019-09-16 | PXD014545 | Pride
Unanchored polyubiquitin chains are emerging as important regulators of cellular physiology with diverse roles paralleling those of substrate-conjugated polyubiquitin. However tools able to discriminate unanchored polyubiquitin chains of different isopeptide linkages have not been described. We desc...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-22 | MSV000079990 | MassIVE
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