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UnknownIntrathecal delivery of a bicistronic AAV9 vector expressing β-hexosaminidase A corrects Sandhoff disease in a murine model: A dosage study.
Not available
S-EPMC10777117 | biostudies-literature
ProteomicsNaive and DSS Murine Colon TMTpro bRP fractionation N-terminomics
The mammalian lysosomal protease legumain is often dysregulated in pathophysiological conditions including inflammation, neurodegeneration, and cancer, yet its proteolytic targets are poorly defined. To profile protease substrates degradomics techniques typically employ enrichment strategies to sele...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-29 | PXD060852 | Pride
Mouse Protease Fractionation Legumain N-terminomics Colon Colitis 
UnknownProcessing of DNA single-strand breaks with oxidatively damaged ends by LIG1.
Not available
S-EPMC12693511 | biostudies-literature
UnknownSequential dietary exposure to aflatoxin B1 and fumonisin B1 in F344 rats increases liver preneoplastic changes indicative of a synergistic interaction.
Not available
S-EPMC5010177 | biostudies-literature
UnknownA novel sampling method to detect airborne influenza and other respiratory viruses in mechanically ventilated patients: a feasibility study.
Not available
S-EPMC5904094 | biostudies-literature
UnknownMicroRNA-16 sensitizes breast cancer cells to paclitaxel through suppression of IKBKB expression.
Not available
S-EPMC5029655 | biostudies-literature
UnknownLATS kinase-mediated CTCF phosphorylation and selective loss of genomic binding.
Not available
S-EPMC7030924 | biostudies-literature
UnknownAnalysing calcium signalling of cells under high shear flows using discontinuous dielectrophoresis.
Not available
S-EPMC4648442 | biostudies-literature
UnknownAn incoherent feedforward loop interprets NFκB/RelA dynamics to determine TNF-induced necroptosis decisions.
Not available
S-EPMC7734648 | biostudies-literature
MetabolomicsCyclooxygenase-2, Asymmetric Dimethylarginine, and the Cardiovascular Hazard From Nonsteroidal Anti-Inflammatory Drugs (Murine and human plasma quantitative L-arginine and methylarginines UPLC-MS/MS assay)

BACKGROUND: Large-scale, placebo-controlled trials established that nonsteroidal anti-inflammatory drugs confer a cardiovascular hazard: this has been attributed to depression of cardioprotective products of cyclooxygenase (COX)-2, especially prostacyclin. An alternative mechanis...

2019-08-22 | MTBLS685 | MetaboLights
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