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UnknownExperimental infection of Z:ZCLA Mongolian gerbils with human hepatitis E virus.
Not available
S-EPMC4299338 | biostudies-literature
MetabolomicsClinical efficacy of Yiqi Yangxue formula on knee osteoarthritis and unraveling therapeutic mechanism through plasma metabolites in rats.

OBJECTIVE: To observe the clinical efficacy and safety of Yiqi Yangxue formula (YQYXF) on knee osteoarthritis (KOA), and to explore the underlying therapeutic mechanism of YQYXF through endogenous differential metabolites and their related metabolic pathways.

METHOD...

2024-03-25 | MTBLS5667 | MetaboLights
UnknownAssociation of Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA4) Gene Polymorphisms with Autoimmune Thyroid Disease in Children and Adults: Case-Control Study.
Not available
S-EPMC4844099 | biostudies-literature
ProteomicsMetabolomics in pancreatic cancer cells influenced by MTHFD2
Metabolomics of pancreatic cancer cell are modified by metabolic enzyme MTHFD2. SW1990 cells were transfected with MTHFD2 siRNA and control siRNA. Cells were collected for metabolomics analysis.
ORGANISM(S): Homo Sapiens 
2021-02-18 | PXD024228 |
Proteomicshuman PFKFB3 immunoprecipitates LC-MS/MS Raw DATA
Flag-PFKFB3 was expressed in SW1990 cells. Immunoprecipitation analysis was performed using the anti-Flag antibody, and the extracts were analyzed by mass spectrometry.
ORGANISM(S): Homo Sapiens 
2019-12-09 | PXD016644 |
ProteomicsCBX4 contributes to HIV-1 latency by forming phase-separated nuclear bodies and SUMOylating EZH2
Molecular mechanisms of HIV-1 latency have been studied extensively to achieve a functional cure for the acquired immunodeficiency syndrome (AIDS). To develop more promising latency-reversing agents (LRAs) to efficiently reactivate the latent reservoir which is subsequently eliminated by immune surv...
ORGANISM(S): Homo Sapiens 
2022-01-14 | PXD031011 |
UnknownSelective targeting of MYC mRNA by stabilized antisense oligonucleotides.
Not available
S-EPMC8627489 | biostudies-literature
TranscriptomicsInfection of apple by Apple stem grooving virus leads to extensive alterations in gene expression patterns but no disease symptoms
To understand the molecular basis of viral diseases, transcriptome profiling has been widely used to correlate host gene expression change patterns with disease symptoms during viral infection in many plant hosts. We used infection of apple by Apple stem grooving virus (ASGV), which produces no dise...
ORGANISM(S): Malus domestica 
2014-04-17 | E-GEOD-53825 | biostudies-arrayexpress
UnknownCBX4 contributes to HIV-1 latency by forming phase-separated nuclear bodies and SUMOylating EZH2
Not available
S-SCDT-EMBOR-2021-53855-T | biostudies-other
ProteomicsCAF-1 promotes HIV-1 latency by leading the formation of phase-separated suppressive nuclear bodies
HIV-1 latency is a major obstacle to achieve a functional cure for AIDS. To eradicate the viral reservoir, one of the strategies is to specifically reactivate HIV-1-infected cells and followed by elimination with potent immune surveillance. However, present latency-reversing agents (LRAs) are quite ...
ORGANISM(S): Homo Sapiens 
2021-02-09 | PXD024172 |
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