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TranscriptomicsThe Tasmanian devil transcriptome reveals Schwann cell origins of a clonally transmissible cancer (small RNA sequencing)
The Tasmanian devil, a marsupial carnivore, is endangered due to the emergence of a clonally transmissible cancer known as Devil Facial Tumor Disease (DFTD). This fatal cancer is clonally derived and is an allograft transmitted between devils by biting. We performed a large-scale genetic analysis of...
ORGANISM(S): Sarcophilus harrisii 
2010-01-01 | E-GEOD-18352 | biostudies-arrayexpress
ProteomicsTwo of a kind: Transmissible Schwann cell cancers in the endangered Tasmanian devil.
Devil facial tumour disease 1 and 2 (DFT1 and DFT2) are two genetically distinct transmissible cancers endangering the survival of the Tasmanian devil (Sarcophilus harrisii). DFT1 first arose from a cell of the Schwann cell lineage, however, the tissue-of-origin of the recently discovered DFT2 cance...
ORGANISM(S): Sarcophilus harrisii 
2019-08-06 | PXD011209 | Pride
Tasmanian devil Swath Devil facial tumour disease Proteomics 
ProteomicsProteomic analysis of Tasmanian devil facial tumour disease
The Tasmanian devil is the only mammalian species harbouring two lineages of contagious cancer within its population. This dataset represents the proteomics analysis of DFT1, DFT2 and SALEM lines.
ORGANISM(S): Sarcophilus harrisii 
2021-09-09 | PXD021784 | Pride
Dft2 Contagious cancer Devil facial tumour 1 Devil facial tumour 2 Sarcophilus harrisii Tasmanian devil Dft1 
ProteomicsThe ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease
The marsupial Tasmanian devil (Sarcophilus harrisii) faces extinction due to transmissible devil facial tumor disease (DFTD). To unveil the culprit molecular underpinnings, we designed an approach that combines sensitivity to drugs with an integrated systems-biology characterization. Sensitivity to ...
ORGANISM(S): Sarcophilus harrisii 
2019-01-18 | PXD009283 | Pride
Tasmanian devil Dftd Transmissible cancer Erbb 
UnknownTasman-PCR: a genetic diagnostic assay for Tasmanian devil facial tumour diseases.
Not available
S-EPMC6227955 | biostudies-literature
GenomicsTasmanian devil tick microbiome
Bacterial microbiome of ticks collected the Tasmanian devil
PRJEB46057 | ENA
UnknownMolecular characterization of Cryptosporidium and Giardia from the Tasmanian devil (Sarcophilus harrisii).
Not available
S-EPMC5397283 | biostudies-literature
UnknownInbreeding depression in one of the last DFTD-free wild populations of Tasmanian devils.
Not available
S-EPMC7304431 | biostudies-literature
GenomicsTasmanian devil immune tissues
454 sequencing of cDNAs from Tasmanian devil spleen and lymph tissues
PRJEB7940 | ENA
ProteomicsPassage of transmissible cancers in the Tasmanian devil is due to a dominant, shared peptide motif and a limited repertoire of MHC-I allotypes
Transmissible cancers are spread via the passage of malignant cells. The survival of the Tasmanian devil, the largest marsupial carnivore, is threatened by two independent transmissible cancers, devil facial tumour (DFT) 1 and devil facial tumour 2 (DFT2). To aid the development of a peptide vaccine...
ORGANISM(S): Sarcophilus harrisii 
2021-02-08 | PXD020614 | Pride
Contagious cancer Mhc Marsupial Transmissible cancer Tasmanian devil Immunopeptidome 
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