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ProteomicsPassage of transmissible cancers in the Tasmanian devil is due to a dominant, shared peptide motif and a limited repertoire of MHC-I allotypes
Transmissible cancers are spread via the passage of malignant cells. The survival of the Tasmanian devil, the largest marsupial carnivore, is threatened by two independent transmissible cancers, devil facial tumour (DFT) 1 and devil facial tumour 2 (DFT2). To aid the development of a peptide vaccine...
ORGANISM(S): Sarcophilus harrisii 
2021-02-08 | PXD020614 | Pride
Contagious cancer Mhc Marsupial Transmissible cancer Tasmanian devil Immunopeptidome 
UnknownThe newly-arisen Devil facial tumour disease 2 (DFT2) reveals a mechanism for the emergence of a contagious cancer.
Not available
S-EPMC6092122 | biostudies-literature
GenomicsTwo of a kind: Transmissible Schwann cell cancers in the endangered Tasmanian devil
Comparative transcriptome analysis of DFT1, DFT2, and normal Tasmanian devil tissues
PRJEB28680 | ENA
ProteomicsTwo of a kind: Transmissible Schwann cell cancers in the endangered Tasmanian devil.
Devil facial tumour disease 1 and 2 (DFT1 and DFT2) are two genetically distinct transmissible cancers endangering the survival of the Tasmanian devil (Sarcophilus harrisii). DFT1 first arose from a cell of the Schwann cell lineage, however, the tissue-of-origin of the recently discovered DFT2 cance...
ORGANISM(S): Sarcophilus harrisii 
2019-08-06 | PXD011209 | Pride
Tasmanian devil Swath Devil facial tumour disease Proteomics 
GenomicsGenomes of Tasmanian devil transmissible cancers DFT1, DFT2 and normal animals.
The origins and vulnerabilities of two transmissible cancers in Tasmanian devils (2018).
PRJEB21902 | ENA
ProteomicsProteomic analysis of Tasmanian devil facial tumour disease
The Tasmanian devil is the only mammalian species harbouring two lineages of contagious cancer within its population. This dataset represents the proteomics analysis of DFT1, DFT2 and SALEM lines.
ORGANISM(S): Sarcophilus harrisii 
2021-09-09 | PXD021784 | Pride
Dft2 Contagious cancer Devil facial tumour 1 Devil facial tumour 2 Sarcophilus harrisii Tasmanian devil Dft1 
GenomicsRegulation of MHC-I and MHC-II expression by CIITA in transmissible devil facial tumour cells
Transcriptomic analysis of DFT1 and DFT2 cells with overexpression of CIITA
PRJEB45867 | ENA
UnknownTasman-PCR: a genetic diagnostic assay for Tasmanian devil facial tumour diseases.
Not available
S-EPMC6227955 | biostudies-literature
UnknownComparative Cytogenetic Mapping and Telomere Analysis Provide Evolutionary Predictions for Devil Facial Tumour 2.
Not available
S-EPMC7290341 | biostudies-literature
ProteomicsInvestigation of signalling pathways and potential mechanisms of drug resistance associated with the two transmissible cancers in the Tasmanian devil using phosphoproteomics
Investigation of signalling pathways and potential mechanisms of drug resistance associated with the two transmissible cancers in the Tasmanian devil using phosphoproteomics Two transmissible cancers, Devil Facial Tumor 1 (DFT1) and Devil Facial Tumor 2 (DFT2), have caused significant declines in Ta...
ORGANISM(S): Sarcophilus harrisii 
2026-03-09 | PXD058352 | Pride
Kinase inhibitor resistance Receptor tyrosine kinase inhibition Tasmanian devils Transmissible cancer Xenograft Devil facial tumour disease Phosphoproteomics Pdgfr Erbb 
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