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GenomicsEffect of knockdown Tbl1xr1 on gene expression after 2/3 hepatectomy
Effect of knockdown Tbl1xr1 on gene expression after 2/3 hepatectomy
PRJNA1070645 | ENA
ProteomicsMaintenance of β-cell identity through the transcription co-factors TBL1X and TBL1XR1
Diabetes occurs because of inadequate insulin secretion from pancreatic β-cells, relative to insulin requirements. One mechanism explaining β-cell malfunction in diabetes is their loss of identity, maintained by a series of well-defined transcription factors, which activate the transcription of β-ce...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-25 | PXD054677 | Pride
Transcriptional control Tbl1xr1 Cell identity Β-cells Differentiation Pax6 Tbl1x Insulin Diabetes 
GenomicsTBL1XR1 mutations bias germinal center B-cells towards a pro-tumorigenic memory fate
TBL1XR1 mutations bias germinal center B-cells towards a pro-tumorigenic memory fate
PRJNA580268 | ENA
GenomicsTBL1XR1 ensures balanced neural developmental through NCOR complex-mediated regulation of the MAPK pathway
TBL1XR1 ensures balanced neural developmental through NCOR complex-mediated regulation of the MAPK pathway
PRJNA682957 | ENA
UnknownA specific mutation in TBL1XR1 causes Pierpont syndrome.
Not available
S-EPMC4853543 | biostudies-literature
UnknownCorrelations between TBL1XR1 and recurrence of colorectal cancer.
Not available
S-EPMC5353619 | biostudies-literature
UnknownDe novo non-synonymous TBL1XR1 mutation alters Wnt signaling activity.
Not available
S-EPMC5460159 | biostudies-literature
TranscriptomicsEffect of knockdown Tbl1xr1 on gene expression after 2/3 hepatectomy
Our spatiotemporal data confirmed activation of Tbl1xr1 in hepatocytes after 2/3 hepatectomy. TBL1XR1 is a transcriptional cofactor inducing ubiquitination and degradation of NCoR/SMRT co-repressors and NCoR is a negative regulator of hepatocyte proliferation acting through histone deacetylases (HDA...
ORGANISM(S): Mus musculus 
2024-02-05 | GSE254481 | GEO
UnknownTBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate.
Not available
S-EPMC7384961 | biostudies-literature
UnknownDifferent mutations in TBL1XR1 lead to diverse phenotypes of neurodevelopmental disorder: two case reports.
Not available
S-EPMC12117794 | biostudies-literature
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