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ProteomicsProteomic dissection of substrate nanotopography-sensitive mechanotransductive signalling hubs that foster neuronal differentiation.
Neuronal cells are competent in precisely sensing nanotopographical features of their microenvironment and the intrinsic information impacts on neuronal functioning and differentiation “interpreted” by mechanotransductive processes. Attempts to influence and direct neuronal differentiation behaviour...
ORGANISM(S): Rattus norvegicus (Rat) 
2018-01-24 | PXD007644 | Pride
Ngf Mechanotransduction Biomaterial Pc12 cells Zirconia nanosubstrates Cell mechanics Neuronal differentiation Biophysics Shot gun proteomics Quantitative proteomics Integrin signalling 
ProteomicsD6_T30
To examine the signaling pathways active downstream ACKR2, both in constitutive and ligand-stimulated conditions, we carried out a large-scale mass spec-based quantitative phosphoproteomic analysis by SILAC technique. ACKR2 has been expressed in HEK293T cells using a tetracycline-inducible system an...
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD009851 | Pride
Phosphoproteomics d6 t30 silac 
ProteomicsCCR5_T0
To examine the signaling pathways active downstream ACKR2, both in constitutive and ligand-stimulated conditions, we carried out a large-scale mass spec-based quantitative phosphoproteomic analysis by SILAC technique. ACKR2 has been expressed in HEK293T cells using a tetracycline-inducible system an...
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD009866 | Pride
Phosphoproteomics silac ccr5 t0 
ProteomicsCCR5_T30
To examine the signaling pathways active downstream ACKR2, both in constitutive and ligand-stimulated conditions, we carried out a large-scale mass spec-based quantitative phosphoproteomic analysis by SILAC technique. ACKR2 has been expressed in HEK293T cells using a tetracycline-inducible system an...
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD009908 | Pride
Ccr5 t30 phosphoproteomics silac 
ProteomicsD6_T3
To examine the signaling pathways active downstream ACKR2, both in constitutive and ligand-stimulated conditions, we carried out a large-scale mass spec-based quantitative phosphoproteomic analysis by SILAC technique. ACKR2 has been expressed in HEK293T cells using a tetracycline-inducible system an...
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD009835 | Pride
D6 phosphoproteimics silac 
ProteomicsD6_T0
To examine the signaling pathways active downstream ACKR2, both in constitutive and ligand-stimulated conditions, we carried out a large-scale mass spec-based quantitative phosphoproteomic analysis by SILAC technique. ACKR2 has been expressed in HEK293T cells using a tetracycline-inducible system an...
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD009865 | Pride
Phosphoproteomics d6_t0 silac 
ProteomicsZebrafish embryo T18°C MAX QUANT
Effect of temperature variation on zebra fish health and behaviour Water temperature is an important environmental parameter that influences the distribution and the health of fishes. Moreover, temperature has a central role in ectothermic animals affecting their physiology and behaviour. The aim of...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2024-01-26 | PXD009934 | Pride
Shotgun label free zebra fish 
ProteomicsHuman blastoceol fluid LC-MSMS
The objective of this prospective study is to employ proteomic techniques and bioinformatic tools to enlight differences at the protein level in blastocoel fluid of aged and younger woman.
ORGANISM(S): Homo sapiens (Human) 
2017-01-19 | PXD003535 | Pride
Blastocoel fluid Lc-msms Human 
ProteomicsUnravelling the Mechanism of DFO/DpT44mt-Induced Cell Death in breast cancer cells
Iron is required as a cofactor for many critical cellular enzymes involved in energy metabolism and cell proliferation and is thus essential for all living cells. To facilitate the rapid replication, the neoplastic cells have significantly higher levels of ribonucleotide reductase and the transferri...
ORGANISM(S): Homo sapiens (Human) 
2018-04-09 | PXD007595 | Pride
Di-2-pyridylketone 4 Lc/ms-ms analyses. Iron chelator 4-dimethyl-3-thiosemicarbazone Flow cytometry Di-2-pyridylketone thiosemicarbazone scaffold Iron Deferoxamine 
ProteomicsHuman mesenchimal stem cells secretome
The study reports for the first time a quantitative proteomic characterization of the secretome of human bone marrow derived MSC before and after stimulation with a panel of pro-inflammatory cytokines.
ORGANISM(S): Homo sapiens (Human) 
2017-08-11 | PXD005746 | Pride
Human msc secretome 
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