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This study looks at signatures of Aristolochic Acid mutagenesis in bladder cancer, based on exome and whole genome sequencing data. Thirteen bladder tumors and their matched normal DNAs were sequenced on Illumina platforms. Among them eleven were exome sequenced and two were whole genome sequenced.
Data Access Committee EGAC00001000256
Whole genome sequencing dataset of 54 tumor/normal samples of 25 cHCC-ICC cases.
The whole exome sequencing data of 291 tumor/normal samples from 121 cHCC-ICC cases.
The RNA-seq data of 97 tumor samples from 77 cHCC-ICC cases, data of two other HCC tumor samples were also included.
We performed genomic and transcriptomic sequencing of 133 combined hepatocellular and intrahepatic cholangiocarcinoma (cHCC-ICC) cases, including separate, combined, and mixed subtypes.
Data Access Committee EGAC00001001273
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