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TranscriptomicsTranscription profiling by array of primary prostate cancer biopsies wutg different ETS transcription factor rearrangements
This work was conducted to identify shared and specific target genes of different ETS transcription factor rearrangements in prostate cancer. Potential target genes were identified by differential gene expression analysis of primary tumor samples with ETS rearrangements, and validated by ETS silenci...
ORGANISM(S): Homo sapiens 
2014-08-12 | E-GEOD-42954 | biostudies-arrayexpress
TranscriptomicsLarge scale screening for fusion genes in sarcoma patient samples
We have utilized our custom array GPL11054 to screen a set of sarcoma patient samples for fusion genes One negative control was included in the study. We wanted to investigate the power of our fusion-gene array GPL11054 as a means for fusion gene detection in a series of sarcoma patient samples from...
ORGANISM(S): Homo sapiens 
2013-10-23 | E-GEOD-43632 | biostudies-arrayexpress
TranscriptomicsPilot-study for a novel universal tool for detection of oncogenic fusion transcripts
A novel oligonucleotide microarray design is described whereby one can screen for all known oncogenic fusion transcripts by one microarray hybridization. Measurements of chimeric transcript junctions are combined with exon-wise measurements of individual fusion partners. Keywords: Nimblegen custom-...
ORGANISM(S): Homo sapiens 
2010-05-06 | E-GEOD-14435 | biostudies-arrayexpress
UnknownmRNA-Seq and microarray development for the Grooved Carpet shell clam, Ruditapes decussatus: a functional approach to unravel host-parasite interaction.
Not available
S-EPMC4007648 | biostudies-literature
ProteomicsProtein aggregation is an early manifestation of phospholamban p.(Arg14del)-related cardiomyopathy
Background: The p.(Arg14del) pathogenic variant (R14del) of the phospholamban (PLN) gene is a prevalent cause of cardiomyopathy with heart failure. The exact underlying pathophysiology is unknown, and a suitable therapy is unavailable. We aim to identify molecular perturbations underlying this cardi...
ORGANISM(S): Mus musculus (Mouse) 
2021-11-03 | PXD024594 | Pride
Inherited cardiomyopathy Heart failure Phospholamban Protein aggregation 
ProteomicsDifferential proteomic analysis by SWATH-MS unravels the most dominant mechanisms underlying yeast adaptation to nonoptimal temperatures under anaerobic conditions- SWATH data
Elucidation of the mechanism of temperature tolerance in yeast is essential for enhancing cellular robustness of strains, providing more economically and sustainable sound industrial processes. We investigated the differential responses of three distinct Saccharomyces cerevisiae strains, an industri...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-01-04 | PXD016567 | Pride
Yeast Differential expression analysis Anaerobic conditions Swath-ms 
UnknownTreatment of Psoriasis Patients with Latent Tuberculosis Using IL-17 and IL-23 Inhibitors: A Retrospective, Multinational, Multicentre Study.
Not available
S-EPMC10867072 | biostudies-literature
Genomicsena-DATASET-BGI-18-06-2015-05:57:10:511-19 - samples
We sequenced 205 patients who were suffering NSCLC with Exome sequencing method.
EGAD00001001398 | EGA
Genomicsena-DATASET-BGI-18-06-2015-04:55:13:301-17 - samples
We sequenced 292 patients who were suffering NSCLC with Whole genome sequencing or Exome sequencing method.
EGAD00001001397 | EGA
GenomicsFrequent alterations in cytoskeleton remodeling genes in primary and metastatic Chinese lung adenocarcinomas
The landscape of genetic alterations in lung adenocarcinoma derived from Asian patients is largely uncharacterized. Here we present an integrated genomic and transcriptomic analysis of 335 primary lung adenocarcinomas and 35 corresponding lymph node metastases from Chinese patients. Altogether 13 si...
EGAS00001000982 | EGA
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