Sort   by:  
 Page size 
TranscriptomicsTranscription profiling of human eessential thrombocythemia megakaryocytes versus normal megakaryocytes
Normal donors BM CD34+ cells were differentiated in thrombopoietin-treated liquid suspension cultures. Briefly, CD34+ cells (80,000 /mL) were resuspended in a serum-free medium in the presence of 100 ng/mL of human recombinant thrombopoietin (TPO; Genzyme, Boston, MA). Every 3 days, viable cells wer...
ORGANISM(S): Homo sapiens 
2008-06-17 | E-GEOD-997 | biostudies-arrayexpress
TranscriptomicsMYB silencing in CD14-myeloblasts
The c-Myb transcription factor is highly expressed in immature hematopoietic cells and down-regulated during differentiation. To define the role of c-Myb during the terminal differentiation of hematopoietic precursors, we studied the effects of its silencing in human primary CD14-myeloblasts, which ...
ORGANISM(S): Homo sapiens 
2010-07-14 | E-GEOD-21943 | biostudies-arrayexpress
TranscriptomicsNormal counterpart in the identification of a molecular signature for leukemic promyelocytes
Gene expression profiles of 8 samples of CD34+derived normal promyelocytes We collected RNA from CD34+cells from healthy blood donors cultured in serum-free medium with G-CSF, IL-3 and GM-CSF
ORGANISM(S): Homo sapiens 
2014-12-17 | E-GEOD-64282 | biostudies-arrayexpress
TranscriptomicsMYB silencing in CD34+ progenitor cells
The c-Myb transcription factor is highly expressed in immature hematopoietic cells and down-regulated during differentiation. To define the role of c-Myb in human hematopoietic lineage commitment, we studied the effects of its silencing during the commitment of human CD34+ Hematopoietic stem/progeni...
ORGANISM(S): Homo sapiens 
2010-07-14 | E-GEOD-13110 | biostudies-arrayexpress
Transcriptomicshsa-miR-299-5p overexpression in CD34+ hematopoietic progenitor cells
Hemopoiesis entails a series of hierarchically organized events that proceed throughout cell specification and terminates with cell differentiation. Commitment needs the transcription factors effort that, in concert with microRNAs, drives cell fate specification, answering to promiscuous patterns of...
ORGANISM(S): Homo sapiens 
2015-09-20 | E-GEOD-17585 | biostudies-arrayexpress
UnknownSurvival features of EBV-stabilized cells from centenarians: morpho-functional and transcriptomic analyses.
Not available
S-EPMC3528377 | biostudies-literature
UnknownIdentification of miR-31-5p, miR-141-3p, miR-200c-3p, and GLT1 as human liver aging markers sensitive to donor-recipient age-mismatch in transplants.
Not available
S-EPMC5334540 | biostudies-literature
TranscriptomicsTranscription profiling of human hematopoietic stem cell subpopulations
Hematopoietic stem cell (HSC) subsets based on the CD34 expression and/or lineage markers expression
ORGANISM(S): Homo sapiens 
2007-08-03 | E-GEOD-1493 | biostudies-arrayexpress
TranscriptomicsGene expression analysis of human lymphoblastoid cell lines
Human lymphoblastoid cell lines (EBV-immortalised B cells, LcL) obtained from subjects of different age (young 28-40 years, centenarians >95 years) were analysed for gene expression at basal culture conditions and after 48 hours of serum starvation. Lymphoid B cells from centenarians were more resis...
ORGANISM(S): Homo sapiens 
2011-07-29 | E-GEOD-31040 | biostudies-arrayexpress
Sort   by:  
 Page size