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GenomicsSignatures of Aristolochic Acid Mutagenesis in Bladder Cancer
This study looks at signatures of Aristolochic Acid mutagenesis in bladder cancer, based on exome and whole genome sequencing data. Thirteen bladder tumors and their matched normal DNAs were sequenced on Illumina platforms. Among them eleven were exome sequenced and two were whole genome sequenced.
EGAS00001000975 | EGA
ProteomicsPBRM1-deficient PBAF complexes target de novo genomic loci to activate pro-survival genes in clear cell renal cell carcinoma (PBRM1 dataset)
PBRM1 is lost in 40% of clear cell renal cell carcinomas (ccRCC) and the combined loss of VHL and PBRM1 drives ccRCC tumorigenesis. PBRM1 is an accessory subunit of the PBAF subclass of the SWI/SNF chromatin remodeler and despite its well-established role as a tumor suppressor, we have limited under...
ORGANISM(S): Homo Sapiens (human) 
2021-07-24 | PXD020554 | JPOST Repository
ProteomicsPBRM1-deficient PBAF complexes target de novo genomic loci to activate pro-survival genes in clear cell renal cell carcinoma (BRG1 dataset)
PBRM1 is lost in 40% of clear cell renal cell carcinomas (ccRCC) and the combined loss of VHL and PBRM1 drives ccRCC tumorigenesis. PBRM1 is an accessory subunit of the PBAF subclass of the SWI/SNF chromatin remodeler and despite its well-established role as a tumor suppressor, we have limited under...
ORGANISM(S): Homo Sapiens (human) 
2021-07-24 | PXD020553 | JPOST Repository
Genomicsena-DATASET-DUKE-NUS-15-10-2014-08:01:00:925-302 - samples
Description not provided
EGAD00001001036 | EGA
GenomicsDAC for Duke-NUS genomic sequencing projects
Data Access Committee EGAC00001000256
EGAC00001000256 | EGA
Genomics61f6508f-ab66-4d36-ad86-028a0ff97746 - samples
The whole exome sequencing data of 291 tumor/normal samples from 121 cHCC-ICC cases.
EGAD00001005183 | EGA
Genomics77745784-0040-45d2-af14-10f27f05a48d - samples
The RNA-seq data of 97 tumor samples from 77 cHCC-ICC cases, data of two other HCC tumor samples were also included.
EGAD00001005182 | EGA
Genomicseaa4975f-4514-44a7-baa4-9404c42156a2 - samples
Whole genome sequencing dataset of 54 tumor/normal samples of 25 cHCC-ICC cases.
EGAD00001005181 | EGA
GenomicsGenomic and transcriptomic profiling of combined hepatocellular and intrahepatic cholangiocarcinoma reveals distinct molecular subtypes
We performed genomic and transcriptomic sequencing of 133 combined hepatocellular and intrahepatic cholangiocarcinoma (cHCC-ICC) cases, including separate, combined, and mixed subtypes.
EGAS00001003093 | EGA
GenomicsPKU_cHCC-ICC DAC
Data Access Committee EGAC00001001273
EGAC00001001273 | EGA
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