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TranscriptomicsTimEX from human embryonic stem cells, mesenchymal stem cells, and erythroid cells
The organization of mammalian DNA replication is poorly understood. We have produced genome-wide high-resolution dynamic maps of the timing of replication in human erythroid, mesenchymal and embryonic stem cells using TimEX, a method that relies on gaussian convolution of massive, highly redundant d...
ORGANISM(S): Homo sapiens 
2009-11-04 | E-GEOD-18679 | biostudies-arrayexpress
GenomicsAnalysis of interleukin-21-induced Prdm1 gene regulation reveals functional cooperation of STAT3 and IRF4 TFs
Interleukin-21 (IL-21) is a pleiotropic cytokine that induces expression of transcription factor BLIMP1 (encoded by Prdm1), which regulates plasma cell differentiation and T cell homeostasis. We identified an IL-21 response element downstream of Prdm1 that binds the transcription factors STAT3 and I...
ORGANISM(S): Mus musculus 
2010-01-08 | E-GEOD-19198 | biostudies-arrayexpress
ProteomicsEnrichment and mass spectrometry analysis of TbTAX-1-interacting or TbTTC29-interacting proteins by co-immunoprecipitation
Study of Trypanosoma ZMYND12’s ortholog (TbTAX-1) confirmed an axonemal localization of the protein and knockdown of TbTAX-1 using RNAi induced dramatic flagellar motility defects as observed in human. Co-immunoprecipitation assays and ultra-structure expansion microscopy in Trypanosoma brucei then ...
ORGANISM(S): Trypanosoma brucei 
2023-11-01 | PXD039470 | Pride
Trypanosoma Co-immunoprecipitations Flagellar motility Zmynd12 
Genomicsena-DATASET-UCL-ICH-25-11-2015-12:32:35:398-26 - samples
Description not provided
EGAD00001001687 | EGA
GenomicsTelomerase activation by genomic rearrangements in high-risk neuroblastoma
Neuroblastoma is a malignant pediatric tumor of the sympathetic nervous system1. Roughly half of these tumors regress spontaneously or are cured by limited therapy. By contrast, high-risk neuroblastomas have an unfavorable clinical course despite intensive multimodal treatment, and their molecular b...
EGAS00001001308 | EGA
GenomicsDAC University Hospital Cologne
Data Access Committee EGAC00001000361
EGAC00001000361 | EGA
UnknownPATL2 is a key actor of oocyte maturation whose invalidation causes infertility in women and mice.
Not available
S-EPMC5938616 | biostudies-literature
ProteomicsA Multi-Omic Analysis of Human Naive CD4 T cells
Technological advances in genomics, epigenomics, transcriptomics and proteomics have enabled massively parallel measurements across thousands of genes and gene products. Such high-throughput technologies have been extensively used to carry out genome-wide studies particularly in the context of disea...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-04-04 | MSV000079624 | MassIVE
UnknownTobacco, alcohol, cannabis, and illicit drug use and their association with CD4/CD8 cell count ratio in people with controlled HIV: a cross-sectional study (ANRS CO3 AQUIVIH-NA-QuAliV).
Not available
S-EPMC9830769 | biostudies-literature
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