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Proteomics4D label-free proteomics analysis of rat-derived decellularisized polycaprolactone fiber skeleton reinforced biotube and thoracic artery
There is a high clinical demand for developing biological vascular graft that facilitates vascular endothelia and smooth muscle regeneration. Decellularisized extracellular matrix showed bioactive properties in promoting tissue regeneration. In this study, we identified the proteins in rat-derived d...
ORGANISM(S): Rattus norvegicus (Rat) 
2026-02-06 | PXD051651 | Pride
Vascular graft Biotube Thoracic artery Decellularisized 
TranscriptomicsJuvenile obesity in Ossabaw swine produces artery-specific transcriptional changes
We adopted a transcriptome-wide microarray analysis approach to determine the extent to which vascular gene expression is altered as a result of juvenile obesity and identify obesity-responsive mRNAs. We examined transcriptional profiles in the left anterior descending coronary artery (LAD), perivas...
ORGANISM(S): Sus scrofa 
2013-05-29 | E-GEOD-41636 | biostudies-arrayexpress
ProteomicsPhysiological profile of the coronary artery and internal thoracic artery endothelial cells as a basis for the structural and functional congrunce of the arterio-arterial continuum
Currently, it is well established that human endothelial cells (ECs) are characterised by a significant heterogeneity between distinct blood vessels, e.g., arteries, veins, capillaries, and lymphatic vessels. Further, even ECs belonging to the same lineage but grown under different flow patterns (e....
ORGANISM(S): Homo sapiens (Human) 
2023-10-17 | PXD037861 | Pride
Endothelium Pasef Tims tof pro 
TranscriptomicsAdvanced Study of Aortic Pathology (ASAP)
BACKGROUND: The vast majority of thoracic aortic aneurysms (TAAs) are observed either together with a bicuspid aortic valve (BAV), a common congenital disorder, or in idiopathic cases such as patients with a normal tricuspid aortic valve (TAV). The main objective of our study was to identify shared ...
ORGANISM(S): Homo sapiens 
2016-01-15 | E-GEOD-26155 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of human mammary artery media during aging
Our goal was to better understand the genes and pathways implicated during arterial media aging. We therefore compared the gene expression profile of human mammary artery media between Young (<60, 8 patients) and old (>75, 7 patients) patients. The microarray data, generated using the Illumina sentr...
ORGANISM(S): Homo sapiens 
2010-12-07 | E-GEOD-16487 | biostudies-arrayexpress
TranscriptomicsChanges in cardiac transcription profiles following on-pump coronary artery bypass grafting
To investigate changes in cardiac transcription profiles caused by on-pump cardiac surgery, we collected myocardial samples, prior and after grafting, from patients undergoing on-pump coronary artery bypass grafting with cardiopulmonary bypass and cardiac arrest. The transcriptional profile of the m...
ORGANISM(S): Homo sapiens 
2010-07-07 | E-GEOD-12486 | biostudies-arrayexpress
TranscriptomicsMicroRNA profiling by array of Sus scrofa endothelial cells isolated from the athero-protective descending thoracic aorta and the athero-susceptible aortic arch
This study investigates the regional expression profiles of microRNAs (miRNAs) in endothelial cells isolated from the athero-protective descending thoracic aorta (DT) and from the athero-susceptible aortic arch (AA) in a swine model. Seven 2-channel assays comparing DT samples to AA samples were per...
ORGANISM(S): Sus scrofa 
2010-07-16 | E-CBIL-46 | biostudies-arrayexpress
TranscriptomicsThe Stockholm Atherosclerosis Gene Expression (STAGE) study: Global Gene Expression data from coronary and carotid artery disease patients
Tissue samples have been isolated during corornary artery by-pass grafting (CABG)surgery from the atheroscelrotic arterial wall (AAW, aortic root puncture for proxmal ligation of by-pass vessel), non-atherosclertoci arterial wall (NAAW, distal part of mammary artery used a graft for LAD), liver, sk...
ORGANISM(S): Homo sapiens 
2012-08-21 | E-GEOD-40231 | biostudies-arrayexpress
UnknownPedicled versus skeletonized internal thoracic artery grafts: a randomized trial.
Not available
S-EPMC8242404 | biostudies-literature
ProteomicsiTRAQ-based Quantitative Proteomic Analysis of Thoracic Aortic from Adult Rats Born to Pre-eclamptic Mothers
Epidemiological studies suggest that both preeclampsia and gestational hypertension could lead to offspring with vascular dysfunction. Previously, we have analyzed the protein profile of umbilical artery tissue from preeclampsia patients. In order to gain insights into the mechanisms of vascular dys...
ORGANISM(S): Rattus Rattus 
2021-03-18 | PXD024811 |
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