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Gene expression, methylome and splicing of THP-1 monocytic cells and THP-1-derived macrophage
Proteomic studies of macrophage polarization to pro-inflammatory (M1) or tissue reparative (M2) phenotypes has identified interferon-induced proteins with tetratricopeptide repeats (IFIT1, IFIT2 and IFIT3) as potential biomarkers of inflammatory diseases such as atherosclerosis.
ORGANISM(S): Homo sapiens (Human) 
2018-03-15 | PXD008204 | Pride
Monocytes and macrophages are essential components of the innate immune system. Herein, we report that intron retention (IR) plays an important role in the development and function of these cells. Using mRNA sequencing, bioinformatics analyses and RT-qPCR validation, we identified differential IR an...
ORGANISM(S): Homo sapiens 
2019-04-19 | GSE130011 | GEO
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