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ProteomicsRestriction of essential amino acids dictates the systemic response to dietary protein dilution
Dietary protein dilution (DPD) promotes metabolic remodelling and health but the precise nutritional components driving this response remain elusive. Here we demonstrate that dietary amino acids (AA) are sufficient and necessary to drive the response to DPD. In particular, the restriction of dietary...
ORGANISM(S): Mus musculus (Mouse) 
2020-06-15 | PXD018205 | Pride
Essential amino acids Thr biosynthetic 
OtherSite-Specific Ser/Thr/Tyr Phosphoproteome of Sinorhizobium meliloti at Stationary Phase.
Data from ProteomeXchange, PXD ID: PXD002064. File: WT2.mgf. Published as part of PLoS One. 2015 Sep 24;10(9):e0139143 . From the Abstract: {{i}} Sinorhizobium meliloti, a facultative microsymbiont of alfalfa, should fine-tune its cellular processes to live saprophytically in soils characterized wi...
ORGANISM(S): Sinorhizobium_fredii_hh103, Sinorhizobium_meliloti_1021, Sinorhizobium_meliloti_ak83 
GPM32320018836 | GPMDB
Resource Reanalysis 
UnknownA refactored biosynthetic pathway for the production of glycosylated microbial sunscreens.
Not available
S-EPMC11378024 | biostudies-literature
TranscriptomicsMicroarray analysis of S. pyogenes Type M1-CdhA55(-) mutant
A total of 192 genes were found to be differentially expressed; 38 genes of them were up regulated and 154 genes were down regulated. Most notably the functional categories that were affected include carbohydrate metabolism and cell envelop realted genes ( 56, 29.1% of the total),Virulence genes (1...
ORGANISM(S): Streptococcus pyogenes 
2010-10-01 | E-GEOD-15598 | biostudies-arrayexpress
UnknownGenomics-driven discovery of a biosynthetic gene cluster required for the synthesis of BII-Rafflesfungin from the fungus Phoma sp. F3723.
Not available
S-EPMC6518819 | biostudies-literature
UnknownThe Biosynthesis of Capuramycin-type Antibiotics: IDENTIFICATION OF THE A-102395 BIOSYNTHETIC GENE CLUSTER, MECHANISM OF SELF-RESISTANCE, AND FORMATION OF URIDINE-5'-CARBOXAMIDE.
Not available
S-EPMC4447950 | biostudies-literature
TranscriptomicsEffects of KAT2B and WDR5 depletion on hepatocyte gene expression
During fasting, increases in circulating pancreatic glucagon maintain glucose balance by up-regulating hepatic gluconeogenesis. Triggering of the cAMP pathway stimulates the gluconeogenic program through the phosphorylation of CREB and via the de-phosphorylation of the CREB coactivator CRTC2. Hormon...
ORGANISM(S): Mus musculus 
2014-04-21 | E-GEOD-47179 | biostudies-arrayexpress
UnknownEukaryotic-type serine/threonine kinase mediated phosphorylation at Thr169 perturbs mycobacterial guanylate kinase activity.
Not available
S-EPMC5686395 | biostudies-literature
UnknownCapture of micrococcin biosynthetic intermediates reveals C-terminal processing as an obligatory step for in vivo maturation.
Not available
S-EPMC5098666 | biostudies-literature
ProteomicsProteomic studies of es incorporation in S. cattleya WT and ΔbesG strains.
With in vitro biochemical studies showing that βes can be mistranslated for Thr and selectively edited by BesG, we sought to evaluate the ability of BesG to prevent in vivo misincorporation of βes in the native producer S. cattleya. We therefore disrupted the besG gene in S. cattleya and supplied βe...
ORGANISM(S): Streptantibioticus cattleyicolor 
2026-06-08 | PXD073884 | Pride
S. cattleya Beta-ethynylserine 
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