Sort   by:  
 Page size 
ProteomicsPhosphoproteomic analysis of platelets activated by pro-thrombotic oxidized phospholipids and thrombin
Phosphoproteomic analysis of platelets activated by pro-thrombotic oxidized phospholipids and thrombin Alejandro Zimman, Bjoern Titz, Evangelia Komisopoulou, Sudipta Biswas, Thomas G. Graeber, and Eugene A. Podrez ABSTRACT Specific oxidized phospholipids (oxPCCD36) promote platelet hyper-reactivi...
ORGANISM(S): Homo sapiens (Human) 
2013-12-02 | PXD000451 | Pride
Platelets Ltq-orbitrap Phospho-proteomics Human 
UnknownThe effect of high altitude (2500 m) on incremental cycling exercise in patients with pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension: a randomised controlled crossover trial.
Not available
S-EPMC10918318 | biostudies-literature
ProteomicsToxicoproteomics reveals an effect of Clozapine on autophagy in human liver spheroids
Clozapine is an atypical antipsychotic drug for treatment-resistant schizophrenia. Its side effects, including liver enzyme abnormalities, experienced by many patients preclude a more common use as a first-line therapy of schizophrenia. Toxicoproteomics approaches have been demonstrated to effective...
ORGANISM(S): Homo sapiens (Human) 
2022-12-09 | PXD034257 | Pride
Drug-induced liver injury  data-independent acquisition  clozapine  proteomics  systems toxicologydrug-induced liver injury  data-independent acquisition  clozapine  proteomics  systems toxicology 
ProteomicsToxicity of the main electronic cigarette components, propylene glycol, glycerin and nicotine in Sprague Dawley rats in a 90-day OECD inhalation study complemented with molecular endpoints [RNE DATA]
The main constituents of electronic cigarette liquids are nicotine, propylene glycol (PG), and vegetable glycerin (VG), together with distilled water and flavors. To assess the toxicity of PG/VG mixtures with and without nicotine as basic components of liquids used in e-cigarettes, a 90-day rat inha...
ORGANISM(S): Rattus norvegicus (Rat) 
2017-09-11 | PXD006894 | Pride
Respiratory nasal epithelium Rat Itraq Toxicology 
ProteomicsToxicity of the main electronic cigarette components, propylene glycol, glycerin and nicotine in Sprague Dawley rats in a 90-day OECD inhalation study complemented with molecular endpoints [LUNG DATA]
The main constituents of electronic cigarette liquids are nicotine, propylene glycol (PG), and vegetable glycerin (VG), together with distilled water and flavors. To assess the toxicity of PG/VG mixtures with and without nicotine as basic components of liquids used in e-cigarettes, a 90-day rat inha...
ORGANISM(S): Rattus norvegicus (Rat) 
2017-09-11 | PXD005959 | Pride
Rat Electronic cigarette Lung 
ProteomicsToxicity of the main electronic cigarette components, propylene glycol, glycerin and nicotine in Sprague Dawley rats in a 90-day OECD inhalation study complemented with molecular endpoints [LIVER DATA]
The main constituents of electronic cigarette liquids are nicotine, propylene glycol (PG), and vegetable glycerin (VG), together with distilled water and flavors. To assess the toxicity of PG/VG mixtures with and without nicotine as basic components of liquids used in e-cigarettes, a 90-day rat inha...
ORGANISM(S): Rattus norvegicus (Rat) 
2017-09-11 | PXD005958 | Pride
Rat Electronic cigarette Lung 
UnknownRight ventricular strain impairment due to hypoxia in patients with COPD: a post hoc analysis of two randomised controlled trials.
Not available
S-EPMC11752043 | biostudies-literature
ProteomicsRespiratory effects of exposure to aerosol from the candidate modified-risk tobacco product THS 2.2 in an 18-month systems toxicology study with A/J mice [Lung data]
Smoking cessation is the most effective measure for reducing the risk of smoking-related diseases but switching to less harmful products (modified-risk tobacco products) can be an alternative for smokers who would otherwise not quit. In an 18-month chronic carcinogenicity/toxicity study in A/J mice ...
ORGANISM(S): Mus musculus (Mouse) 
2020-08-13 | PXD016460 | Pride
Lc-msms Mouse Lung Systems toxicology Itraq 
UnknownEffect of low-flow oxygen therapy on 6 minute walk test in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension: a randomized non-inferiority crossover trial.
Not available
S-EPMC13537019 | biostudies-literature
ProteomicsRespiratory effects of exposure to aerosol from the candidate modified-risk tobacco product THS 2.2 in an 18-month systems toxicology study with A/J mice [RNE data]
Smoking cessation is the most effective measure for reducing the risk of smoking-related diseases but switching to less harmful products (modified-risk tobacco products) can be an alternative for smokers who would otherwise not quit. In an 18-month chronic carcinogenicity/toxicity study in A/J mice ...
ORGANISM(S): Mus musculus (Mouse) 
2020-08-13 | PXD016466 | Pride
Lc-msms Respiratory nasal epithelium Mouse Systems toxicology Itraq 
Sort   by:  
 Page size