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ProteomicsQuantitative serum proteomics of monogamous deer mice (Peromyscus) reveals systemic alterations driven by pair-bonding and bond disruption
This dataset contains TMT-10plex quantitative proteomics of serum isolated from monogamous deer mice (Peromyscus). The study investigates the systemic physiological impact of social interactions, specifically comparing pair-bonded animals to those that have experienced bond disruption. The circulati...
ORGANISM(S): Peromyscus 
2026-06-23 | PXD079929 | Pride
Deer mouse Social stress Bond disruption Pair-bonding Tmt-10plex Peromyscus Serum Circulating liquidome Gene canalization 
ProteomicsTMT-10plex-based phosphoproteomics of bioactive compounds in A549 cells
We conducted a comprehensive screening of bioactive compounds sourced from natural products, specifically targeting those capable of inducing apoptosis while inhibiting tyrosine kinase activity. Our investigation encompassed a diverse range of compounds, including pure compounds, compound mixtures, ...
ORGANISM(S): Homo sapiens (Human) 
2024-03-13 | PXD050555 | Pride
Post translational modification Lc-ms/ms Phosphorylation Apoptosis Lung epidermal cells Isobaric mass tag Egfr 
ProteomicsHuman Hippocampus from Non-Hispanic Whites and African Americans with and without Alzheimer's disease LC-MS3
This study examined global proteomic changes in postmortem hippocampus tissue from Non-Hispanic Whites and African American individuals who were cognitively normal or had Alzheimer's disease using LC-MS3 on an Orbitrap Fusion Lumos. Proteins were quantified in the LC-MS3 experiments using Tandem Mas...
ORGANISM(S): Homo sapiens (Human) 
2020-10-19 | PXD012114 | Pride
Human Brain Hippocampus Tmt Lc-ms3 
ProteomicsHuman Globus Pallidus (GP) from Non-Hispanic Whites and African Americans with and without Alzheimer's disease LC-MS3
This study examined global proteomic changes in postmortem globus pallidus (GP) tissue from Non-Hispanic Whites and African American individuals who were cognitively normal or had Alzheimer's disease using LC-MS3 on an Orbitrap Fusion Lumos. Proteins were quantified in the LC-MS3 experiments using T...
ORGANISM(S): Homo sapiens (Human) 
2020-10-19 | PXD014371 | Pride
Human Globus pallidus Brain Tmt Alzheimer's disease Lc-ms3 
UnknownTandem Mass Tag-10plex (TMT-10plex) phosphoproteomics dataset for comprehensive analysis of active compounds with tyrosine kinase inhibition activity.
Not available
S-EPMC11214987 | biostudies-literature
ProteomicsTMT-10plex analysis of endogenous proteins expressed in HEK-293 cells as a recombinant transporter assay system
Tandem-mass-tags (TMT)-10plex proteomics characterized endogenous proteins expressed in HEK-293 cells transiently transfected with control vector or transporter cDNA. Proteomic profiles between mock (n=3), naïve (n=3), and HEK-293 cells transfected with MATE1 cDNA (1, 10, 30, 100 ng) were compared.
ORGANISM(S): Homo Sapiens (human) 
2022-07-07 | PXD030022 | JPOST Repository
ProteomicsProbing the Molecular Phenotype of the Transgenerational Ischemia-Resilient Retina
A comparative analysis of the proteome of mouse retina with and without ischemic injury and hypoxia conditioning was achieved through discovery-based quantitative proteomics. Retina from each mouse were harvested immediately for Quantitative Discovery-Based Proteomic Workflow. A 10plex TMT experimen...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-08 | PXD014769 | Pride
Retina mouse ischemia hypoxia tmt quantitative proteomics 
ProteomicsU251 Supernatent for TMT Normalization
Supernatant analysis from pY enrichment. Supernatent used to normalize TMT-10plex data.
ORGANISM(S): Homo sapiens (Human) 
2018-11-29 | PXD008940 | Pride
Ptx U251 Vbl 
ProteomicsSERUM DATA FILES EMI TB PROTEOMICS
Five complete TMT10plex labellings including active TB patients and infected and uninfected contacts
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-04-01 | MSV000083645 | MassIVE
ProteomicsComparison of DIA and TMT based protein quantification in complex background
Label free quantification (LFQ) and isobaric labelling quantification (ILQ) are among the most popular protein quantification workflows in discovery proteomics. Here, we compared the TMT 10-plex workflow to label free single shot data-independent acquisition (DIA) method on a controlled sample set. ...
ORGANISM(S): Mus musculus (Mouse) 
2019-01-24 | PXD011691 | Pride
Tmt Orbitrap fusion lumos Dia 
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