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ProteomicsTNAP - a potential cytokine in the cerebral inflammation in Spastic Cerebral Palsy
Our study was designed to pinpoint the chief molecule playing the specific and critical role in the neuroinflammation in spastic CP, which may provide promising target for diagonosis and treatment of spastic CP. To further our exploration, our future study will focus on the molecular mechanism of ho...
ORGANISM(S): Homo sapiens (Human) 
2022-08-26 | PXD034911 | Pride
Human 
ProteomicsCharacterization of a mitochondria associated phosphocreatine phosphatase in thermogenic adipocytes
Adaptive thermogenesis has attracted much attention because of its ability to raise systemic energy expenditure and counter obesity and diabetes. Recent data have indicated that thermogenic fat cells utilize creatine to stimulate futile substrate cycling, dissipating chemical energy as heat. This mo...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-17 | PXD025032 | Pride
Tnap Thermogenesis Obesity Phosphocreatine Adipocyte 
GenomicsConsequences of decreased TNAP activity during osteogenic differentiation of periodontal ligament cells – a new model for dental defects in hypophosphatasia
Consequences of decreased TNAP activity during osteogenic differentiation of periodontal ligament cells – a new model for dental defects in hypophosphatasia
PRJNA543291 | ENA
UnknownMitochondrial TNAP controls thermogenesis by hydrolysis of phosphocreatine.
Not available
S-EPMC8287965 | biostudies-literature
UnknownApigenin Modulates AnxA6- and TNAP-Mediated Osteoblast Mineralization.
Not available
S-EPMC9658728 | biostudies-literature
UnknownTNAP and P2X7R: New Plasma Biomarkers for Alzheimer's Disease.
Not available
S-EPMC10342008 | biostudies-literature
UnknownTissue Nonspecific Alkaline Phosphatase (TNAP) Regulates Cranial Base Growth and Synchondrosis Maturation.
Not available
S-EPMC5359511 | biostudies-literature
TranscriptomicsConsequences of decreased TNAP activity during osteogenic differentiation of periodontal ligament cells – a new model for dental defects in hypophosphatasia
The effects of TNAP inhibition with levamisole during osteogenic differentiation were analyzed in primary human periodontal ligament cells since patients suffering from hypophosphatasia often display dental symptoms.
ORGANISM(S): Homo sapiens 
2020-04-30 | GSE131338 | GEO
UnknownHaploinsufficient TNAP Mice Display Decreased Extracellular ATP Levels and Expression of Pannexin-1 Channels.
Not available
S-EPMC5841270 | biostudies-literature
UnknownTNAP dephosphorylates phosphocholine and phosphoethanolamine and participates in triglyceride transport from the liver to the bloodstream.
Not available
S-EPMC12559424 | biostudies-literature
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