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ProteomicsGFP-Tensin 1 phosphoproteomics upon sodium arsenite treatment in U2OS cells
Tensin 1 (TNS1) is a key component of integrin adhesion and plays a key role in linking the actin cytoskeleton with the ECM through interaction with integrin heterodimers. TNS1 forms functional and reversible condensates in cells in response to different extracellular stimuli that act as reservoirs ...
ORGANISM(S): Homo sapiens (Human) 
2026-04-24 | PXD069806 | Pride
Phosphorylation Protein condensation Integrin adhesions Phase separation Tensin 1 
ProteomicsThe quantitative proteomics analysis of TGF-β induced EMT in A549 cells and TNS-overexpressing A549 cells
Metastasis is the primary cause of mortality in lung cancer patients, with the epithelial-mesenchymal transition (EMT) process conferring increased metastatic potential to carcinoma cells. While emerging evidence suggests that TNS1 contributes to carcinoma metastasis, it remains unclear the role of ...
ORGANISM(S): Homo sapiens (Human) 
2025-12-08 | PXD057161 | Pride
Epithelial-mesenchymal transition (emt) Tns1 Lung cancer Smad3 Zeb1 
UnknownLncRNA MAGI2-AS3 inhibits bladder cancer progression by targeting the miR-31-5p/TNS1 axis.
Not available
S-EPMC7803496 | biostudies-literature
UnknownA positive feedback loop between TNS1 and ZEB1 promotes TGFβ-induced epithelial-to-mesenchymal transition in lung cancer.
Not available
S-EPMC12657872 | biostudies-literature
ProteomicsAdhesion-derived condensates control component availability to regulate adhesion dynamics
Tensins are key components of integrin adhesions and play a key role in linking the actin cytoskeleton with the ECM through interaction with integrin heterodimers. While tensin 1 (TNS1) localises to both focal and fibrillar adhesions, TNS3 has been mostly associated with fibrillar adhesions. Tensins...
ORGANISM(S): Homo sapiens (Human) 
2026-04-24 | PXD069837 | Pride
Protein condensation Integrin adhesions Tensin 3 Phase separation Tensin 1 
UnknownHigh miR-31-5p expression promotes colon adenocarcinoma progression by targeting TNS1.
Not available
S-EPMC7202535 | biostudies-literature
UnknownImmunohistochemical Analysis of the Expression of Adhesion Proteins: TNS1, TNS2 and TNS3 in Correlation with Clinicopathological Parameters in Gastric Cancer.
Not available
S-EPMC8146480 | biostudies-literature
UnknownTNS1 and NRXN1 Genes Interacting With Early-Life Smoking Exposure in Asthma-Plus-Eczema Susceptibility.
Not available
S-EPMC10643854 | biostudies-literature
UnknownRNA-Binding Protein COL14A1, TNS1, NUSAP1 and YWHAE Are Valid Biomarkers to Predict Peritoneal Metastasis in Gastric Cancer.
Not available
S-EPMC9062106 | biostudies-literature
UnknownTensin 1 (TNS1) is a modifier gene for low body mass index (BMI) in homozygous [F508del]CFTR patients.
Not available
S-EPMC8176904 | biostudies-literature
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