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ProteomicsThe genome of North American beaver provides insights into the mechanisms of its longevity and cancer resistance
Comparative proteome analysis of beaver (Castor canadensis) and mouse (Mus musculus) liver tissues
ORGANISM(S): Castor canadensis Mus musculus (Mouse) 
2022-02-16 | PXD028546 | Pride
Cancer Longevity Comparative biology Aging 
ProteomicsA rare human centenarian variant of SIRT6 enhances genome stability and interaction with Lamin A
Sirtuin 6 (SIRT6) is a deacylase and mono-ADP ribosyl transferase (mADPr) enzyme involved in multiple cellular pathways implicated in the regulation of aging and metabolism. Targeted sequencing identified a SIRT6 allele containing two linked substitutions (N308K/A313S) as enriched in Ashkenazi Jewis...
ORGANISM(S): Homo sapiens (Human) 
2022-10-21 | PXD035689 | Pride
Lmna Centenarian Longevity Sirt6 Adp-ribosylation Aging 
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