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MetabolomicsExploring the Glucose Fluxotype of the E. coli y-ome Using High-Resolution Fluxomics
We have developed a robust workflow to measure high-resolution fluxotypes (metabolic flux phenotypes) for large strain libraries under fully controlled growth conditions. This was achieved by optimizing and automating the whole high-throughput fluxomics process and integrating all relevant software ...
2021-05-13 | MTBLS2188 | MetaboLights
MetabolomicsMetabolic profiling of prostate cancer in skeletal microenvironments identifies G6PD as a key mediator of growth and survival

The spread of cancer to bone is invariably fatal, with complex cross-talk between tumor cells and the bone microenvironment responsible for driving disease progression. By combining in silico analysis of patient datasets with metabolomic profiling of prostate cancer cells cultured with bone cells...

2024-08-19 | MTBLS3973 | MetaboLights
UnknownContinuing versus withdrawing ixekizumab treatment in patients with axial spondyloarthritis who achieved remission: efficacy and safety results from a placebo-controlled, randomised withdrawal study (COAST-Y).
Not available
S-EPMC8292566 | biostudies-literature
ProteomicsProteome profiling of cultivated Echerichia coli isolates from Crohn's disease patients
One of the dysbioses often observed in CD patients is an increased abundance of Escherichia coli (10-100 fold compared to healthy individuals) [Gevers et al., 2014]. E. coli isolates collected from CD and healthy patients were cultivated on LB medium at aerobic conditions up to medium log phase and...
ORGANISM(S): Escherichia coli 
2019-08-15 | PXD010920 | Pride
Crohn's disease Hplc-ms/ms Proteome E. coli 
UnknownBCG vaccine may generate cross-reactive T cells against SARS-CoV-2: In silico analyses and a hypothesis.
Not available
S-EPMC7440160 | biostudies-literature
TranscriptomicsTranscription profiling of post-mortem human brain to investigate gender specific gene expression
Gender differences in brain development and in the prevalence of neuropsychiatric disorders such as depression have been reported. Gender differences in human brain might be related to patterns of gene expression. Microarray technology is one useful method for investigation of gene expression in bra...
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-2164 | biostudies-arrayexpress
ProteomicsProteomic analysis in transgenic hybrid aspen (Populus tremula x tremuloides) trees overexpression of vesicle-associated membrane protein PttVAP27-17
In this study we report on transgenic hybrid aspen (Populus tremula x P. tremuloides) lines that showed potential to increase biomass production both in the greenhouse and after five years of growth in the field. The transgenic lines carried an overexpression construct for Populus tremula x tremuloi...
ORGANISM(S): Populus tremula x Populus tremuloides 
2021-09-10 | PXD023826 | Pride
Hdmse Wood Populus 
ProteomicsA proteomics approach reveals function of Secretory Carrier-Associated Membrane Proteins in wood formation of Populus trees
Secretory Carrier-Associated Membrane Proteins (SCAMPs) are highly conserved 32–38 kDa proteins that are involved in membrane trafficking. A proteomics approach was taken to elucidate function of the SCAMPs in wood formation of transgenic Populus trees carrying an RNAi construct for Populus tremula ...
ORGANISM(S): Populus tremula x Populus tremuloides 
2018-01-10 | PXD008266 | Pride
Hdmse Wood formation Populus Xylem 
UnknownGene cloning and molecular characterization of lysine decarboxylase from Selenomonas ruminantium delineate its evolutionary relationship to ornithine decarboxylases from eukaryotes.
Not available
S-EPMC111417 | biostudies-literature
UnknownX11 proteins regulate the translocation of amyloid beta-protein precursor (APP) into detergent-resistant membrane and suppress the amyloidogenic cleavage of APP by beta-site-cleaving enzyme in brain.
Not available
S-EPMC2602917 | biostudies-literature
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