Sort   by:  
 Page size 
TranscriptomicsTranscription profiling by array of human trabecular meshwork cells to investigate the molecular mechanisms by which MYOC mutants cause glaucoma
Comparison of human trabecular meshwork transcriptomes of cells glaucoma-linked MYOC mutant Q368X
ORGANISM(S): Homo sapiens 
2012-10-06 | E-MEXP-3427 | biostudies-arrayexpress
TranscriptomicsConstitutively active RhoA (RhoAV14) expression and regulation of acqeous humor outflow dynamics
Impaired drainage of aqueous humor through the trabecular meshwork (TM) culminating in increased intraocular pressure is a major risk factor for glaucoma, a leading cause of blindness worldwide. Regulation of aqueous humor drainage through the TM, however, is poorly understood. The role of RhoA GTPa...
ORGANISM(S): Homo sapiens 
2010-05-19 | E-GEOD-9288 | biostudies-arrayexpress
TranscriptomicsMYOC.R342KvsNull
Comparison of human trabecular meshwork transcriptomes of cells overexpressing glaucoma-linked MYOC mutant R342K
ORGANISM(S): Homo sapiens 
2012-09-08 | E-MEXP-3435 | biostudies-arrayexpress
TranscriptomicsMYOC.K423EvsNull
Comparison of human trabecular meshwork transcriptomes of cells overexpressing glaucoma-linked MYOC mutant K423E
ORGANISM(S): Homo sapiens 
2012-10-06 | E-MEXP-3439 | biostudies-arrayexpress
TranscriptomicsMYOC.WTvsNull
Comparison of human trabecular meshwork transcriptomes of cells overexpressing wild-type Myocilin
ORGANISM(S): Homo sapiens 
2012-10-06 | E-MEXP-3440 | biostudies-arrayexpress
TranscriptomicsMYOC.D380NvsNull
Comparison of human trabecular meshwork transcriptomes of cells overexpressing glaucoma-linked MYOC mutant D380N
ORGANISM(S): Homo sapiens 
2012-09-08 | E-MEXP-3434 | biostudies-arrayexpress
MetabolomicsSphingolipid Analysis of hyper and normotensive DBA2J mice aqueous humor and trabecular meshwork
Not available
ORGANISM(S): Mus musculus 
ST000620 | MetabolomicsWorkbench
TranscriptomicsTranscription profiling of human trabecular meshwork cultured cells, non-glaucomatous and POAG tissue
The goal of this study was to contrast genome-wide gene expression profiles of cultured human trabecular meshwork (HTM) cells, to that of control and primary open angle glaucoma (POAG) HTM tissues. Total RNA from cultured HTM cells and HTM tissue dissected from control and POAG anterior segments fix...
ORGANISM(S): Homo sapiens 
2008-06-13 | E-GEOD-4316 | biostudies-arrayexpress
ProteomicsAutophagy the key player in trabecular meshwork death-mechanistic difference in early and advanced glaucoma
This study highlights the differential roles of apoptosis versus autophagy in cell death mechanism in the trabecular meshwork in primary adult glaucoma at various stages. This reflects the possible role of autophagy in causing glaucomatous damage in severe disease stages
ORGANISM(S): Homo sapiens (Human) 
2021-09-08 | PXD010752 | Pride
Poag Glaucoma Autophagy Trabecular meshwork Proteomics Pacg 
TranscriptomicsComparison of gene expression profile of human trabecular meshwork cells induced by triamcinolone with dexamethasone
PURPOSE. Triamcinolone acetonide (TA) and dexamethasone (DEX) are corticosteroids commonly used for ocular inflammation but both can cause ocular hypertension. We investigated the differential gene expression profile of human trabecular meshwork (TM) cells in response to treatment by TA compared to ...
ORGANISM(S): Homo sapiens 
2008-05-01 | E-GEOD-6298 | biostudies-arrayexpress
Sort   by:  
 Page size