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To explore the mechanism underlying the negative regulation of adipogenesis by TRAF4, we performed the LC-MS/MS experiments to identify the proteins that interact with TRAF4 during adipogenic differentiation.
ORGANISM(S): Homo sapiens (Human) 
2020-05-27 | PXD017524 | Pride
Total RNA-Seq in control and TRAF4-overexpressing LNCaP cells
Genome-wide AR binding under androgen deprivation condition upon TRAF4 overexpression
TRAF4 promotes the malignancy of ovarian high-grade serous carcinoma by activating YAP pathway
Insects use innate immunity to defend microbial infection. Toll pathway is a major immune signaling pathway that is associated with antifungal immune response in mosquitoes. Our study identified a fungal-induced deubiquitinase, OTU7B, which, when knocked out, promotes the translocation of the NF-κB ...
ORGANISM(S): Aedes Aegypti 
2022-11-22 | PXD038261 |
Ovarian high-grade serous carcinoma (HGSC) accounts for the majority of deaths caused by epithelial ovarian cancer. The precise molecular changes attributable for the pathogenesis of HGSC are still largely unknown. TRAF4 has been identified to be up-regulated in some cancers. However, the associatio...
ORGANISM(S): Homo sapiens 
2022-05-15 | GSE202840 | GEO
Evaluation of mRNA expression changes upon TRAF4 mis-expression in HT1376 and T24 bladder cancer cell lines
We reported the total gene expression in control and TRAF4-overexpressing LNCaP cells
ORGANISM(S): Homo sapiens 
2023-02-17 | GSE225509 | GEO
TRAF4 is highly expressed in the epithelial bladder cancer cell line, HT1376 and poorly expressed in the mesenchymal cell line, T24. We evaluated the genetic changes in HT1376 upon TRAF4 knockdown using two independent shRNAs targetting TRAF4. The changes were documented with respect to the control ...
ORGANISM(S): Homo sapiens 
2020-11-16 | GSE161509 | GEO
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