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MetabolomicsTranslational repression of viral RNA mediates arbovirus persistence in mosquitoes

Persistent infection of mosquito vectors is essential for the transmission of arboviruses, yet how these viruses produce sufficient progeny without compromising host cell fitness remains unclear. Arbovirus genomes exhibit suboptimal codon usage for both human and mosquito hosts, raising questions...

2026-02-12 | MTBLS12760 | MetaboLights
MetabolomicsInositol Pyrophosphates Mediate Chloroplast Lipid Remodeling and Nuclear Gene Repression during High-Light Acclimation in Chlamydomonas reinhardtii
Microalgae are photosynthetic organisms capable of autotrophic growth. Their applicability in multiple industrial fields has been largely studied, thanks to their ability to fixate CO2 into high added value organic products like fatty acids and carotenoids. However, our under-standing of the cellula...
2026-06-09 | MTBLS14720 | MetaboLights
ProteomicsProtein Lysine 43 Methylation by EZH1 Promotes AML1-ETO Transcriptional Repression
The MS data of Protein Lysine 43 Methylation by EZH1 Promotes AML1-ETO Transcriptional Repression Protein Lysine 43 Methylation by EZH1 Promotes AML1-ETO Transcriptional Repression
ORGANISM(S): Homo Sapiens 
2019-12-11 | PXD016712 |
TranscriptomicsA large intergenic non-coding RNA induced by p53 mediates global gene repression in the p53 transcriptional response
Recently, more than a thousand large intergenic non-coding RNAs (lincRNAs) have been reported. These RNAs are evolutionarily conserved in mammalian genomes and thus presumably function in diverse biological processes. Here, we report the identification of lincRNAs that are regulated by p53. One of ...
ORGANISM(S): Mus musculus 
2010-08-09 | E-GEOD-21761 | biostudies-arrayexpress
TranscriptomicsA network of transcriptional repression specifies muscle fibre type in the zebrafish embryo
The zebrafish u-boot (ubo) gene encodes the transcription factor Prdm1, which is essential for the specification of the primary slow twitch muscle fibres that derive from adaxial cells. Here we show that Prdm1 executes this function by acting as a transcriptional repressor. Expression of the slow tw...
ORGANISM(S): Danio rerio 
2010-05-25 | E-GEOD-10883 | biostudies-arrayexpress
ProteomicsTranscriptional repression activity of androgen receptor targets cell plasticity in prostate cancer: BioID analysis
Androgen receptor (AR) signaling remains the key therapeutic target in the management of hormone-naïve advanced prostate cancer (PCa) and castration-resistant PCa (CRPC). Recently, landmark molecular features have been reported for CRPC, including the expression of constitutively active AR variants ...
ORGANISM(S): Homo sapiens (Human) 
2022-10-14 | PXD029454 | Pride
Androgen receptor  ar-v7  cell plasticity  prostate cancer  emt  transcriptional repression 
ProteomicsTranscriptional repression activity of androgen receptor targets cell plasticity in prostate cancer: kinetic analysis after DHT treatment
Androgen receptor (AR) signaling remains the key therapeutic target in the management of hormone-naïve advanced prostate cancer (PCa) and castration-resistant PCa (CRPC). Recently, landmark molecular features have been reported for CRPC, including the expression of constitutively active AR variants ...
ORGANISM(S): Homo sapiens (Human) 
2022-10-13 | PXD029520 | Pride
Androgen receptor  ar-v7  cell plasticity  prostate cancer  emt  transcriptional repression 
TranscriptomicsTranscriptional response of steady-state Escherichia coli cultures to a glucose pulse, in order to elucidate the role of post-transcriptional regulation during carbon catabolite repression
Gene-expression measurements were made over a 60 minute time course as steady state E. coli cells were subjected to a pulse of glucose.
ORGANISM(S): Escherichia coli 
2015-06-29 | E-MTAB-2398 | biostudies-arrayexpress
ProteomicsHigh-density CRISPRi screens reveal adaptive transcriptional gradients in cyanobacteria
Cyanobacteria are the oldest form of photosynthetic life and contribute to primary production in nearly every habitat, from permafrost to hot springs. Despite longstanding interest in the biochemical basis of environmental adaptation in these microbes, it remains poorly understood. Here we used a hi...
ORGANISM(S): Synechococcus Sp. Pcc 7002 (ncbitaxon:32049) 
2024-04-18 | MSV000094564 | MassIVE
ProteomicsMBD8 is required for LDL2-mediated transcriptional repression downstream of H3K9me2 in Arabidopsis
Histone H3 lysine 9 methylation (H3K9me) is a conserved epigenetic mark for transcriptional gene repression. In Arabidopsis, H3K9 dimethylation (H3K9me2) promotes the removal of a transcription-associated mark, H3K4 monomethylation (H3K4me1), and this process within genes requires the histone demeth...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2026-06-08 | PXD069014 | Pride
Arabidopsis Ldl2 Mbd8 
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