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ProteomicsCompetitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma
The pluripotency transcription factor SOX2 is essential for the maintenance of glioblastoma stem cells (GSC), which drive tumor growth and treatment resistance.To understand how SOX2 is regulated in GSCs, we utilized a proteomic approach and identified the E3 ubiquitin ligase TRIM26...
ORGANISM(S): Homo sapiens (Human) 
2021-11-04 | PXD028933 | Pride
Glioblastoma Trim26 E3 ligase Wwp2 Brain cancer Sox2 
TranscriptomicsRNA-sequencing of human adherent glioblastoma stem cell line following RNA interference targeting TRIM26
RNA-sequencing (Ribo-ZERO, Illumina HiSeq-2500, single-end 50 bp reads) was on human glioblastoma stem cells (B67) performed 5 days after lentivirus transduction with MISSION TRC lentiviruses using control scrambled (sh002) or two distinct TRIM26 RNAi (TRCN0000004050 (sh4050) and TRCN0000004051 (sh4...
ORGANISM(S): Homo sapiens 
2021-08-31 | E-MTAB-10899 | biostudies-arrayexpress
GenomicsRNA-sequencing of human adherent glioblastoma stem cell line following RNA interference targeting TRIM26
RNA-sequencing of human adherent glioblastoma stem cell line following RNA interference targeting TRIM26
PRJEB47232 | ENA
UnknownThe Multifunction of TRIM26: From Immune Regulation to Oncology.
Not available
S-EPMC11475100 | biostudies-literature
UnknownTRIM26 facilitates PRV infection through NDP52-mediated autophagic degradation of MAVS.
Not available
S-EPMC11225307 | biostudies-literature
UnknownTRIM26 alleviates fatal immunopathology by regulating inflammatory neutrophil infiltration during Candida infection.
Not available
S-EPMC10786383 | biostudies-literature
UnknownTRIM26 deficiency enhancing liver regeneration through macrophage polarization and β-catenin pathway activation.
Not available
S-EPMC11208526 | biostudies-literature
UnknownTRIM26 Facilitates HSV-2 Infection by Downregulating Antiviral Responses through the IRF3 Pathway.
Not available
S-EPMC7825454 | biostudies-literature
UnknownTRIM26 inhibited osteosarcoma progression through destabilizing RACK1 and thus inactivation of MEK/ERK signaling.
Not available
S-EPMC10435491 | biostudies-literature
UnknownCompetitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.
Not available
S-EPMC8566473 | biostudies-literature
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