Trna-derived fragment

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4x(2)H labeled dimethylated residue (1)

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Proteomics Platform CIC bioGUNE, Bizkaia Tec. Park Build. 800, derio 48160 Bizkaia (Spain) (1)
Qilu Hospital of Shandong University (1)

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Guanosine-7 tRNA methylation steers tRNA-derived fragment biogenesis and translational control in prostate cancer

PRJNA788918 | ENA

METTL1 promotes tumorigenesis through tRNA-derived fragment biogenesis in prostate cancer

PRJNA962138 | ENA

tRNA fragment profiling in CLP1 mutant (kinase-dead) mice

Loss of CLP1 activity results in the accumulation of novel sets of small RNA fragments derived from aberrant processing of tyrosine pre-tRNA. Such tRNA fragments sensitize cells to oxidative stress-induced p53 activation and p53-dependent cell death. 2 samples, Wt and Clp1(k/k), no replicates

ORGANISM(S): Mus musculus

2013-04-03 | E-GEOD-39275 | biostudies-arrayexpress

Serum tRNA-derived fragment and tRNA half profiles across chronic atrophic gastritis, early gastric cancer, and gastric cancer

PRJNA1513039 | ENA

Fragmentation of mitochondrial mt-tRNA-LeuTAA provides a regulator of metabolic physiology

In this study, we discovered cytosolic and mitochondrial fragments resulting from tRNA and mt-tRNA cleavage, which may act as new regulators of cellular and metabolic functions. We selected the mt-tRF-LeuTAA fragment derived from a tRNA encoded by the mitochondrial genome for further investigation, ...

ORGANISM(S): Rattus norvegicus (Rat)

2024-06-16 | PXD046117 | Pride

Guanosine-7 tRNA methylation steers tRNA-derived fragment biogenesis and translational control in prostate cancer

Transfer RNAs (tRNAs) are exceptionally subject to modifications, including methylation. While mRNA methylation is emerging as an important regulator of biological and pathological processes in cancer, how post-transcriptional methylation of tRNAs contributes to cancer is largely unknown. Here we sh...

ORGANISM(S): Homo sapiens (Human)

2023-10-24 | PXD030141 | Pride

Cancer Rna modifications 7-methylguanosine Prostate cancer Trnas Trna fragments Epitranscriptome Protein synthesis Translatome

Guanosine-7 tRNA methylation steers tRNA-derived fragment biogenesis and translational control in prostate cancer

PRJNA784954 | ENA

Study of the tRNA-derived fragment expression profile in rat pancreatic islets of diabetes-susceptible low-protein (LP) exposed rats

PRJNA1001870 | ENA

Study of the tRNA-derived fragment expression profile in mouse pancreatic islets of pre-diabetic obese db/db mice

PRJNA1000965 | ENA

A nuclear tRNA-derived fragment triggers immunity in Arabidopsis.

Not available

S-EPMC11962134 | biostudies-literature

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