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Mutations in TRPS1 cause trichorhinophalangeal syndrome types I and III, which are characterized by sparse scalp hair in addition to craniofacial and skeletal abnormalities. Trps1 is a vertebrate transcription factor containing nine zinc-finger domains, including a GATA-type zinc finger through whi...
ORGANISM(S): Mus musculus 
Identification of TRPS1 interactors in MCF7, T47D and ZR75-1 breast cancer cell lines.
ORGANISM(S): Homo sapiens (Human) 
2018-06-12 | PXD009863 | Pride
TRPS1 was recently identified as a radiation marker in breast cancer. In order to characterise the molecular phenotype that is associated with TRPS1 we knocked out the gene in two radiation-transformed breast cell lines.
ORGANISM(S): Homo sapiens 
Yes-associated protein (YAP), the downstream transducer of the Hippo pathway is a key regulator of organ size, differentiation and tumourigenesis. Yet, the activity of YAP can also be modulated by Hippo-independent functions. To disclose these Hippo-independent regulators, we performed a genome-wide...
ORGANISM(S): Homo sapiens (Human) 
2018-08-09 | PXD009819 | Pride
TRPS1 regulates estrogen-receptor binding and histone acetylation at enhancers
TRPS1 mutant (R544Q) regulates epithelial to mesenchymal transition
TRPS1 impairs myogenic differentiation in embryonal rhabdomyosarcoma [ChIP-seq]
TRPS1 drives heterochromatic origin refiring and cancer genome evolution
Gene expression by TRPS1 knocked down in T47D
Trps1 predicts poor prognosis in advanced high grade serous ovarian carcinoma
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