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UnknownPreclinical trials in autosomal dominant AD: implementation of the DIAN-TU trial.
Not available
S-EPMC3880800 | biostudies-literature
ProteomicsLoss of lysosomal acid lipase results in mitochondrial dysfunction and fiber switch in skeletal muscles of mice
Objective: Lysosomal acid lipase (LAL) is the only enzyme known to hydrolyze cholesteryl esters (CE) and triacylglycerols in lysosomes at an acidic pH. Despite the importance of lysosomal hydrolysis in skeletal muscle (SM), research in this area is limited. We hypothesized that LAL may play an impor...
ORGANISM(S): Mus musculus (Mouse) 
2024-01-26 | PXD045665 | Pride
Muscle proteomics Lal Lal deficiency Energy metabolism Lal-deficient mouse 
UnknownSurvey of Diabetes Technology in the Pediatric Inpatient Setting.
Not available
S-EPMC11809535 | biostudies-literature
TranscriptomicsLong Noncoding RNA MALAT1 Controls Cell Cycle Progression by Regulating the Expression of Oncogenic Transcription Factor B-MYB
The long noncoding MALAT1 RNA is upregulated in cancer tissues and its elevated expression is associated with hyper-proliferation, but the underlying mechanism is poorly understood. We demonstrate that MALAT1 levels are regulated during normal cell cycle progression. Genome-wide transcriptome analys...
ORGANISM(S): Homo sapiens 
2014-05-16 | E-GEOD-44240 | biostudies-arrayexpress
MetabolomicsPlasma metabolite changes in dairy cows during parturition identified using untargeted metabolomics
The metabolic responses of cows undergo substantial changes during the transition from late pregnancy to early lactation. However, the molecular mechanisms associated with these changes in physiological metabolism have not been clearly elucidated. The objective of this study was to investigate metab...
2019-08-20 | MTBLS809 | MetaboLights
ProteomicsTECPR2 HSAN9 Mutation Medulla analysis Mouse
Analysis of proteome changes in medulla in mice expressing a disease-mimicking TECPR2 variant
ORGANISM(S): Mus musculus (Mouse) 
2025-10-23 | PXD065944 | Pride
Proteomics medulla tecpr2 
UnknownZSF1 rat as animal model for HFpEF: Development of reduced diastolic function and skeletal muscle dysfunction.
Not available
S-EPMC7524062 | biostudies-literature
TranscriptomicsGlobal transcriptome analysis of the pH regulator pacC in Colletotrichum gloeosporioides
Colletotrichum gloeosporioides, a widely distributed economically important agent in postharvest fruit disease thrives by massive secretion of ammonia to alkalize its environment and activate its pathogenicity genes. We sequenced the C. gloeosporioides transcriptomes of WT and a M-bM-^HM-^FpacC muta...
ORGANISM(S): Colletotrichum gloeosporioides 
2013-11-21 | E-GEOD-41844 | biostudies-arrayexpress
UnknownLoss of lysosomal acid lipase results in mitochondrial dysfunction and fiber switch in skeletal muscles of mice.
Not available
S-EPMC7615526 | biostudies-literature
UnknownNonalcoholic fatty liver disease stratification by liver lipidomics.
Not available
S-EPMC8488246 | biostudies-literature
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