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Study goal is to disclose features of gene expressio profile of non-cancerous liver-infiltrating lymphocytes of type C hepatitis patients with hepatocellular carcinomas and tumor-infiltrating lymphocytes of type C hepatitis patients with hepatocellular carcinomas. Keywords: gene expression profile,...
ORGANISM(S): Homo sapiens 
The accumulation of acidic metabolic waste products within the tumor microenvironment profoundly inhibits effector functions of tumor-infiltrating lymphocytes (TILs). However, it is unclear whether extracellular-acidosis impacts T cell metabolic fitness and differentiation status. Here, we surprisin...
2023-01-17 | MTBLS6661 | MetaboLights
The IGR-Heu tumor cell line was established from patient Heu suffering from large cell carcinoma of the lung. Heu171, Heu127 and Heu161 T cell clones were isolated from autologous tumor infiltrating lymphocytes. H32 T cell line and H32-22 clone were isolated from autologous PBL after stimulation wit...
ORGANISM(S): Homo sapiens 
The IGR-Heu tumor cell line was established from patient Heu suffering from large cell carcinoma of the lung. Heu171 T cell clones were isolated from autologous tumor infiltrating lymphocytes. H32-22 clone was isolated from autologous peripheral blood lymphocytes after stimulation with IGR-Heu and...
ORGANISM(S): Homo sapiens 
We had previously demonstrated the role of CD103 integrin on lung tumor-infiltrating lymphocyte (TIL) clones in promoting specific TCR-mediated epithelial tumor cell cytotoxicity. However, the contribution of CD103 on intratumoral T-cell distribution and functions, and the prognosis significance of ...
ORGANISM(S): Homo sapiens 
A retrospective tissue study to explore the prognostic significance of tumor-infiltrating lymphocyte (TIL) populations in Nasopharyngeal Cancer, using a combination of RNA sequencing and immunohistochemistry.
ORGANISM(S): Homo sapiens 
Tumor infiltrating lymphocytes (TILs) play a significant role in the tumor microenvironment in high-grade serous ovarian cancer (HGSOC). To better understand the interactions and functions of TILs in HGSOC progression, we performed proteogenomic profiling of TILs in 65 tumors collected from 12 HGSOC...
ORGANISM(S): Homo sapiens (Human) 
2024-03-15 | PXD045710 | Pride
Microbial organisms play key roles in numerous physiological processes in the human body and have recently been shown to modify the response to cancer radiotherapy and immune checkpoint inhibitors. Here, we demonstrate that HLA molecules of both glioblastoma tissues as well as tumor cell lines prese...
ORGANISM(S): Homo sapiens (Human) 
2023-02-20 | PXD036811 | Pride
Whole mouse genome microarrays from Agilent were used to determine expression profile of pancreas-infiltrating T CD3+ and total T lymphocytes of NOD mice.
ORGANISM(S): Mus musculus 
The microRNA oligo microarrays from Agilent were used to determine miRNA expression profile of pancreas-infiltrating T CD3+ and total T lymphocytes of NOD mice.
ORGANISM(S): Mus musculus 
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