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Epstein-Barr virus (EBV) has a lifelong latency period after initial infection. Rarely, however, when the EBV immediate early gene BZLF1 is expressed by a specific stimulus, the virus switches to the lytic cycle to produce progeny viruses. We found that EBV infection reduced levels of various cerami...
2023-12-20 | MTBLS7649 | MetaboLights
Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide, with chronic hepatitis B virus (HBV) infection being a major contributor to its development. Despite this, effective treatment for HBV-associated HCC remains a significant challenge. In this study, we combined the s...
2025-07-17 | MTBLS12196 | MetaboLights
Children are at high risk for influenza A virus (IAV) infections, which can develop into severe illnesses. However, little is known about interactions between the microbiome and respiratory tract metabolites and their impact on the development of IAV pneumonia in children. Using a combination of liq...
2024-09-25 | MTBLS4816 | MetaboLights
Previously we reported that a recombinant vaccinia virus (VACV) carrying a light-emitting fusion gene enters, replicates in, and reveals the locations of tumors in mice. A new recombinant VACV, GLV-1h68, as a simultaneous diagnostic and therapeutic agent, was constructed by inserting three expressio...
ORGANISM(S): Mus musculus 
Rice stripe virus (RSV) is one of the major virus diseases of rice in East Asia. Rice plants infected with RSV usually show symptoms such as chlorotic leaf stripes, weakness and senescence of leaves, and dwarfism. In order to characterize the host response to RSV infection at the gene expression lev...
ORGANISM(S): Oryza sativa Japonica Group 
Detection/identification of virola proteins from tumor cells
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2015-02-12 | MSV000079036 | MassIVE
Susceptible and Resistant mouse strain, e.g. DBA/2J and C57BL/6J respectively, were inoculated with a highly pathogenic H5N1 influenza A virus (A/Hong Kong/213/2003) for 72 hours. Differences in expression were analyzed and use to identify candidate genes and pathways that contributed to the differe...
ORGANISM(S): Mus musculus 
This is a mathematical model describing the treatment of tumors using oncolytic virus and chemotherapy. The model is comprised of nonlinear ordinary differential equations describing the interactions between uninfected tumor cells, infected tumor cells, an oncolytic virus, and chemotherapy.
2024-09-02 | BIOMD0000000877 | BioModels
This mathematical model is described by the publication: Rommelfanger DM, Offord CP, Dev J, Bajzer Z, Vile RG, Dingli D. "Dynamics of melanoma tumor therapy with vesicular stomatitis virus: explaining the variability in outcomes using mathematical modeling". Gene Ther. 2012 May;19(5):543-9. doi: 10....
2021-09-11 | MODEL2109110003 | BioModels
This mathematical model is described by the publication: Rommelfanger DM, Offord CP, Dev J, Bajzer Z, Vile RG, Dingli D. "Dynamics of melanoma tumor therapy with vesicular stomatitis virus: explaining the variability in outcomes using mathematical modeling". Gene Ther. 2012 May;19(5):543-9. doi: 10....
2021-09-11 | MODEL2109110004 | BioModels
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