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ProteomicsChemical proteomics reveals protein tyrosination extends beyond the alpha-tubulins in human cells.
Tubulin detyrosination-tyrosination cycle regulates the stability of microtubules. Thus far described on α-tubulins, the tyrosination level is maintained by a single tubulin-tyrosine ligase (TTL). However, the precise dynamics and tubulin isoforms which undergo (de)tyrosination in neurons are unknow...
ORGANISM(S): Homo sapiens (Human) 
2022-10-20 | PXD037402 | Pride
Ingns Dia-nn Tyrosination Sp2e Sh-sy5y 
ModelsGrignard2022 - Detyrosination/Tyrosination Model in neurons and proliferative cells
SBML files for the mathematical model from the publication "Mathematical modeling of the microtubule detyrosination/tyrosination cycle for cell-based drug screening design"
2022-10-15 | MODEL2209260001 | BioModels
UnknownChemical Proteomics Reveals Protein Tyrosination Extends Beyond the Alpha-Tubulins in Human Cells.
Not available
S-EPMC10099736 | biostudies-literature
UnknownMathematical modeling of the microtubule detyrosination/tyrosination cycle for cell-based drug screening design.
Not available
S-EPMC9236252 | biostudies-literature
UnknownStructural basis of tubulin tyrosination by tubulin tyrosine ligase.
Not available
S-EPMC3563685 | biostudies-literature
UnknownCrosstalk between acetylation and the tyrosination/detyrosination cycle of α-tubulin in Alzheimer's disease.
Not available
S-EPMC9459041 | biostudies-literature
UnknownTubulin tyrosination regulates synaptic function and is disrupted in Alzheimer's disease.
Not available
S-EPMC9337816 | biostudies-literature
UnknownThe role of α-tubulin tyrosination in controlling the structure and function of hippocampal neurons.
Not available
S-EPMC9627282 | biostudies-literature
UnknownChronic Activation of Tubulin Tyrosination Improves Heart Function.
Not available
S-EPMC11465905 | biostudies-literature
UnknownEffects of microtubule (de)tyrosination on the morphology and motility of Trypanosoma brucei and cross-talk with polyglutamylation.
Not available
S-EPMC12714142 | biostudies-literature
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