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ProteomicsProteomic analysis of U251 MG glioblastoma cells in the presence and absence of α-fodrin
The cortical cytoskeleton comprises mainly of the spectrin family of proteins. Spectrin and fodrin are members of this family. They support the plasma membrane. Fodrin is expressed in most tissues apart from the erythrocytes. Fodrin has been shown to be important in a wide variety of functions such ...
ORGANISM(S): Homo sapiens (Human) 
2021-05-24 | PXD023457 | Pride
Α-fodrin Lc-ms Shrna U251 mg glioblastoma cells 
TranscriptomicsGenomic analyses reveal miR-137 broad impact on genes associated with malignant transformation and neuronal differentiation in glioblastoma cells
miR-137 plays critical roles in the nervous system and tumor development. An increase in its expression is required for neuronal differentiation while its reduction is implicated in gliomagenesis. To evaluate the potential of miR-137 in glioblastoma therapy, we conducted genome-wide target mapping i...
ORGANISM(S): Homo sapiens 
2014-02-11 | E-GEOD-53220 | biostudies-arrayexpress
ProteomicsReverse phase protein arrays (RPPAs): effects of MPS1 inhibition on signaling pathways in GBM cells
To determine the biological effects of MPS1 inhibition (both by siRNA and Drug (NMSP715)) on signaling pathways in GBM cells (U251 &U87), we profiled the modulation of phosphorylated and non-phosphorylated proteins using RPPA Relative protein levels for each sample were determined by interpolation o...
ORGANISM(S): Homo sapiens 
2015-06-25 | E-GEOD-67502 | biostudies-arrayexpress
UnknownPLEKHG5 regulates autophagy, survival and MGMT expression in U251-MG glioblastoma cells.
Not available
S-EPMC7736842 | biostudies-literature
UnknownPharmacological Inhibition of Membrane Signaling Mechanisms Reduces the Invasiveness of U87-MG and U251-MG Glioblastoma Cells In Vitro.
Not available
S-EPMC9954756 | biostudies-literature
Genomicsa New Marine-Derived Asterosaponin (CN-3) alleviated the proliferation of U251 MG cells
a New Marine-Derived Asterosaponin (CN-3) alleviated the proliferation of U251 MG cells
PRJNA423237 | ENA
TranscriptomicsMicroarray analysis of human gene expression in metronomic cyclophosphamide-treated human glioma U251 xenografts implanted in scid mice
Cyclophosphamide (CPA) treatment on a six-day repeating metronomic schedule induces a dramatic, innate immune cell-dependent regression of implanted gliomas. However, little is known about the underlying mechanisms of innate immune cell mobilization and recruitment, or about the role of DNA damage a...
ORGANISM(S): Homo sapiens 
2015-05-04 | E-GEOD-60867 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of mouse gene expression in metronomic cyclophosphamide-treated human glioma U251 xenografts implanted in scid mice
Cyclophosphamide (CPA) treatment on a six-day repeating metronomic schedule induces a dramatic, innate immune cell-dependent regression of implanted gliomas. However, little is known about the underlying mechanisms of innate immune cell mobilization and recruitment, or about the role of DNA damage a...
ORGANISM(S): Homo sapiens 
2015-05-04 | E-GEOD-60866 | biostudies-arrayexpress
TranscriptomicsHuman Mesenchymal Stem Cells Exploit the Immune Response Mediating Chemokines to Impact the Phenotype of Glioblastoma
Four human mesenchymal stem cells (hMSC) clones (MSC-1, MSC-2, MSC-3, MSC-4) and three different glioblastoma multiformae (GBM) cell lines (U87-MG, U251, U373) were used to study their mutual paracrine interactions in the indirect co-cultures compared to their monocultures, which were grown under th...
ORGANISM(S): Homo sapiens 
2011-12-20 | E-GEOD-26283 | biostudies-arrayexpress
Transcriptomicsa New Marine-Derived Asterosaponin (CN-3) alleviated the proliferation of U251 MG cells
Analysis of U251 glioblastoma multiforme (GBM) cells treated with a new culcita novaeguineae asterosaponion, CN-3. A new asterosaponin was isolated from culcita novaeguineae, an abundant marine resource in the south China sea. The asterosaponin induced significant growth inhibition with a 50% inhibi...
ORGANISM(S): Homo sapiens 
2020-06-16 | GSE108343 | GEO
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