Umbilical cord stromal cells

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CHEBI ID

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CHEBI:29016 (2)
CHEBI:17154 (2)
CHEBI:16908 (2)
CHEBI:16347 (2)
CHEBI:16919 (2)
CHEBI:16335 (2)
CHEBI:17552 (2)
CHEBI:16027 (2)
CHEBI:28300 (2)
CHEBI:16761 (2)
CHEBI:15741 (2)

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(3E)-3-Benzylidene-4-Methyl-1H-1,4-Benzodiazepine-2,5-Dione (1)
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5,10-Dimethoxy-2,2-Dimethylpyrano[3,2-G]Chromen-8-One (1)
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Study type

Transcription profiling by array (79)
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Release Date

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Lab affiliation

CNC - Center for Neuroscience and Cell Biology, University of Coimbra (1)
Department of Clinical Medicine, University of Tromsø 9037 Tromsø, Norway (1)
Department of Hematopoiesis, Sanquin Research, Amsterdam, The Netherlands (1)
Gonçalo Moniz Institute, FIOCRUZ, Salvador, Brazil D'Or Institute for Research and Education (IDOR), Salvador, Brazil Center for Biotechnology and Cell Therapy, São Rafael Hospital, Salvador, Brazil (1)
Shanghai Children Medical Center, School of Medicine, Shanghai Jiao Tong University (1)

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Human umbilical cord-derived mesenchymal stem cells ameliorate perioperative neurocognitive disorder by inhibiting inflammatory responses and activating BDNF/TrkB/CREB signaling pathway in aged mice

BACKGROUND: Perioperative neurocognitive disorder (PND) is a key complication affecting older individuals after anesthesia and surgery. Failure to translate multiple pharmacological therapies for PND from preclinical studies to clinical settings has necessitated the exploration o...

2023-07-25 | MTBLS7759 | MetaboLights

Mesenchymal stromal cells secretome restores bioenergetic and redox homeostasis in human proximal tubule cells after ischemic injury

BACKGROUND: Ischemia/reperfusion injury (IRI) is the leading cause of acute kidney injury (AKI). The current standard of care focuses on supporting kidney function, stating the need for more efficient and targeted therapies to enhance repair. Mesenchymal Stromal Cells (MSCs) and ...

2023-10-16 | MTBLS6279 | MetaboLights

Gene expression profile of mesenchymal stem cells from paired umbilical cord units: cord is different from blood

Mesenchymal stem cells (MSC) are multipotent cells which can be obtained from several adult and fetal tissues including human umbilical cord units. We have recently shown that umbilical cord tissue (UC) is richer in MSC than umbilical cord blood (UCB) but their origin and characteristics in blood a...

ORGANISM(S): Homo sapiens

2009-09-18 | E-GEOD-18134 | biostudies-arrayexpress

Microarray of neural progenitor cells from neonatal lung injury mice treated with placebo or umbilical-cord mesenchymal stromal cell extracellular vesicles or untreated, as well as age-matched control mice

The purpose of this experiment was to determine the transcriptional differences between neural progenitor cells from neonatal lung injury mice vs. control mice, as well as neonatal lung injury mice treated with umbilical-cord mesenchymal stromal cell extracellular vesicles vs. neonatal lung injury m...

ORGANISM(S): Mus musculus

2022-05-17 | E-MTAB-11157 | biostudies-arrayexpress

Large-scale secretome analyses unveil a superior immunosuppressive phenotype from umbilical cord stromal cells compared to other adult mesenchymal stromal cells

Mesenchymal stromal cells (MSCs) with regenerative and immunomodulatory potential are being investigated as a potential therapeutic tool for cartilage lesions. MSCs express a wide variety of bioactive molecules including cytokines, trophic factors, and proteases, which act in a paracrine fashion to ...

ORGANISM(S): Homo sapiens (Human)

2019-01-29 | PXD011762 | Pride

Transcription profiling by array of differences between multipotent stromal cells isolated from human bone marrow, umbilical cord blood and placenta

Unrestricted somatic stem cells (USSCs) from human cord blood show distinct differences to multipotent stromal cells isolated from human bone marrow and placenta both at the gene array and functional level. Fibroblast samples and raw data also included in E-TABM-724.

ORGANISM(S): Homo sapiens

2014-11-26 | E-TABM-880 | biostudies-arrayexpress

Proteomic analysis of human Wharton's jelly mesenchymal stem cells and human amniotic epithelial stem cells: a comparison of therapeutic potential

proteomics analysis of human umbilical cord mesenchymal stem cells and human amniotic epithelial stem cells

ORGANISM(S): Homo Sapiens

2024-06-05 | PXD052844 |

Global gene expression analysis of human embryonic stem cells, adult fibroblasts , and CD34+ cord blood (CB) cells before, during, and afer their episomal induction of pluripotency

Global gene expression analysis of (a) human embryonic stem cells, (b) adult fibroblasts with and without nucleofection of SOKM, and ( c ) CD34+ cord blood cells at various time points during induction of pluripotency with SOKM, with or without co-culture with bone marrow stromal cells (BMSC). Total...

ORGANISM(S): Homo sapiens

2012-08-23 | E-GEOD-35027 | biostudies-arrayexpress

Expression data from mesenchymal stromal cells isolated from the umbilical cord tissue (UCXM-BM-.) and cultivated in ATMP-compatible media

Standardization of MSC manufacturing is urgently needed to facilitate comparison of clinical trial results. Here, we compare gene expression of MSC generated by the adaptation of a proprietary method for isolation and cultivation of a specific umbilical cord tissue-derived population of Mesenchymal ...

ORGANISM(S): Homo sapiens

2013-12-16 | E-GEOD-51869 | biostudies-arrayexpress

Human umbilical cord matrix mesenchymal stem cells suppress the growth of breast cancer by expression of tumor suppressor genes [human]

Human and rat umbilical cord matrix mesenchymal stem cells (UCMSC) possess the ability to control the growth of breast carcinoma cells. Comparative analyses of two types of UCMSC suggest that rat UCMSC-dependent growth regulation is significantly stronger than that of human UCMSC. Their different tu...

ORGANISM(S): Homo sapiens

2015-08-06 | E-GEOD-64827 | biostudies-arrayexpress

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