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ProteomicsIP-to-MS: an unbiased workflow for antigen profiling
Immunoprecipitation is among the most widely utilized methods in biomedical research, with applications that include the identification of antibody targets and associated proteins. The path to identifying these targets is not straightforward, however, and often requires the use of chemical crosslink...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD056617 | Pride
Autoimmune disease Mass spectrometry Unbiased antigen identification Immunoprecipitation 
GenomicsSuitability of formalin-fixed paraffin-embedded tumor tissue for unbiased tumor-associated antigen identification
Suitability of formalin-fixed paraffin-embedded tumor tissue for unbiased tumor-associated antigen identification
PRJNA671877 | ENA
UnknownIP-to-MS: An Unbiased Workflow for Antigen Profiling.
Not available
S-EPMC11812086 | biostudies-literature
ProteomicsTOFIMS mass spectrometry-based immunopeptidomics refines tumor antigen identification
T cell recognition of human leukocyte antigen (HLA)-presented tumor-associated peptides is central for cancer immune surveillance. Mass spectrometry (MS)-based immunopeptidomics represents the only unbiased method for directly identifying and characterizing naturally presented tumor-associated pepti...
ORGANISM(S): Homo sapiens (Human) 
2023-11-21 | PXD038782 | Pride
Hla Benign immunopeptidome Tumor antigen Mass spectrometry Timstof Immunopeptidome 
ProteomicsIdentification of gastric cancer associated serum antibodies using Helicobacter pylori antigen microarrays
Unbiased de-novo identification of biomarkers for H.pylori associated gastric cancer; Microarrays, representing 242 seroreactive H.pylori proteins, were generated by spotting of the respective gene constructs and cell-free on-chip expression. Antibody levels to these proteins were measured by appli...
ORGANISM(S): Homo sapiens 
2020-09-14 | E-MTAB-9534 | biostudies-arrayexpress
UnknownUnbiased Identification of Immunogenic Staphylococcus aureus Leukotoxin B-Cell Epitopes.
Not available
S-EPMC7093132 | biostudies-literature
UnknowncopepodTCR: Identification of Antigen-Specific T Cell Receptors with combinatorial peptide pooling.
Not available
S-EPMC10705480 | biostudies-literature
TranscriptomicsSuitability of formalin-fixed paraffin-embedded tumor tissue for unbiased tumor-associated antigen identification
For the effectiveness of targeted immunotherapy, which is currently one of the most promising treatments for brain tumors, it is necessary to know specific tumor-associated antigens (TAA). This project aimed to validate the suitability of formalin-fixed and paraffin-embedded (FFPE) material instead ...
ORGANISM(S): Canis lupus familiaris 
2020-10-27 | GSE160124 | GEO
TranscriptomicsThe Microbial Detection Array Combined with Random Phi29-Amplification used as a Diagnostic Tool for Unbiased Virus Detection in Clinical Samples
A common technique used for sensitive and specific diagnostic virus detection in clinical samples is PCR. However, an unbiased diagnostic microarray containing probes for all human pathogens could replace hundreds of individual PCR-reactions and remove the need for a clear clinical hypothesis regard...
ORGANISM(S): Homo sapiens 
2011-04-14 | E-GEOD-28597 | biostudies-arrayexpress
Proteomics2E7 Antigen Identification Using PhAbomics Technology
Antibody–drug conjugates (ADCs) require antibodies with both high specificity and efficient internalization—features often overlooked by conventional discovery pipelines that rely on preselected antigens and recombinant proteins. Here, we present an integrated phenotypic platform that combines targe...
ORGANISM(S): Homo sapiens (Human) 
2025-11-20 | PXD065365 | Pride
Antibody Antigen Cell-based antibody panning 
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