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TranscriptomicsWidespread Generation of Alternative UTRs Contributes to Sex-specific RNA Binding by UNR
Upstream of N-ras (UNR) is a conserved RNA-binding protein that regulates mRNA translation and stability by binding to sites generally located in untranslated regions (UTRs). In Drosophila, sex-specific binding of UNR to msl2 mRNA and the non-coding RNA roX plays key roles in the control of X-chromo...
ORGANISM(S): Drosophila melanogaster 
2011-10-25 | E-GEOD-33178 | biostudies-arrayexpress
TranscriptomicsiCLIP transcriptome-wide mapping of UNR (CSDE1) binding sites
Analysis of UNR (CSDE1) binding to RNA targets by iCLIP transcriptome-wide mapping.
ORGANISM(S): Homo sapiens 
2016-11-07 | E-MTAB-3818 | biostudies-arrayexpress
ProteomicsProtein interaction partners of drosophila Unr identified by pull down of wild type and an interdomain mutant protein
To identify an RNP interactome of Unr, V5 tagged wildtype protein and a mutant containing several interdomain contacts, that shows reduced protein expression were tansfected in SL2 cells after a siRNA knoch-down of the endogenous protein levels. After pulling down the transfected protein with an ant...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2020-07-14 | PXD018115 | Pride
Unr Rnp Pull-down Interactome Rbp 
TranscriptomicsWidespread Generation of Alternative UTRs Contributes to Sex-specific RNA Binding by UNR
Upstream of N-ras (UNR) is a conserved RNA-binding protein that regulates mRNA translation and stability by binding to sites generally located in untranslated regions (UTRs). In Drosophila, sex-specific binding of UNR to various RNAs plays key roles in the control of X chromosome dosage compensation...
ORGANISM(S): Drosophila melanogaster 
2011-10-31 | E-GEOD-30963 | biostudies-arrayexpress
TranscriptomicsInactivation of Unr results in induction of differentiation of murine ES cells into the primitive endoderm lineage
Unr (upstream of N-ras) is a cytoplasmic RNA-binding protein with cold shock domains, involved in regulation of messenger RNA stability and translation. To address the biological role of Unr, we inactivated the unr gene by homologous recombination in mice and embryonic stem (ES) cells. Embryos defic...
ORGANISM(S): Mus musculus 
2015-02-10 | E-GEOD-17566 | biostudies-arrayexpress
GenomicsiCLIP transcriptome-wide mapping of UNR (CSDE1) binding sites
iCLIP transcriptome-wide mapping of UNR (CSDE1) binding sites
PRJEB10303 | ENA
GenomicsUnr is a potential post-transcriptional master regulator of protein expression
Unr is a potential post-transcriptional master regulator of protein expression
PRJNA485061 | ENA
TranscriptomicsRibosome profiling of UNR (CSDE1) KD
Investigation of the effects of UNR (CSDE1) knock-down on translation in Melanoma Cells using Ribosome Profiling
ORGANISM(S): Homo sapiens 
2016-11-07 | E-MTAB-3815 | biostudies-arrayexpress
UnknownFunctional domains of Drosophila UNR in translational control.
Not available
S-EPMC2248260 | biostudies-literature
TranscriptomicsUnr is a potential post-transcriptional master regulator of protein expression
Ribonucleoprotein immunoprecipitation followed by mass spectrometry and RNA-Seq was used to investigate the ‘Upstream of N-RAS’ (UNR) protein interactome across three cancer cell lines. A number of novel UNR-interacting proteins and transcripts were discovered, including the ubiquitin E3 ligase, HUW...
ORGANISM(S): Homo sapiens 
2019-08-01 | GSE118279 | GEO
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