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MetabolomicsMetabolomics Study of Serum and Urine Samples Reveals Metabolic Pathways and Biomarkers Associated with Pelvic Organ Prolapse
Pelvic organ prolapse (POP) is a common medical condition among women and involves complicated diagnostics and controversial surgical management. The exact molecular mechanism underlying POP is poorly understood, especially at the metabolism level. To explore the metabolic mechanism underlying POP a...
2019-08-14 | MTBLS1033 | MetaboLights
MetabolomicsUPLC-Q-TOF/MS-Based Plasma and Urine Metabolomics Contribute to the Diagnosis of Sepsis
In this study, we aimed to identify potential metabolic biomarkers that can improve the diagnostic accuracy of sepsis. Sixty-six patients including 30 septic and 36 nonsepsis patients from an intensive care unit were recruited. The global plasma and urine metabolomic profiles were determined by ultr...
2023-04-18 | MTBLS3505 | MetaboLights
ProteomicsSpatiotemporal proteomics of hormone treated mice (urine across time, prostate tissue)
Benign prostatic hyperplasia and related lower urinary tract symptoms remain common, costly, and impactful issues for aging males. Etiology and pathogenesis are multifactorial and include steroid hormone changes and inflammation. Noninvasive markers could one day inform personalized medicine, but in...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-08 | PXD014416 | Pride
Mus musculus Urine Proteomics Hormone Prostate 
ProteomicsUrine proteome analysis in the differential diagnostics of respiratory tract pathology in newbornes under intensive care
To investigate the possibility of using modern mass spectrometric methods for forecasting, early diagnosis of the causes of respiratory diseases, as well as monitoring the effectiveness of treatment of newborns with very low and extremely low birth weight infants. Results: Based on the analysis of l...
ORGANISM(S): Homo sapiens (Human) 
2016-06-21 | PXD001773 | Pride
Preterm newborn Very low birth weight Urine Respiratory tract disorders Neonatal intensive care Proteome 
ProteomicsUrine proteome in patients with metabolic associated fatty liver disease
Background Metabolic associated fatty liver disease (MAFLD) was recently proposed to replace non-alcoholic fatty liver disease (NAFLD), which is defined as ectopic fat deposition in the liver. Hepatic steatosis is an independent predictor for insulin resistance and cardiovascular risk and hence mor...
ORGANISM(S): Homo sapiens (Human) 
2022-08-12 | PXD026333 | Pride
Metabolic associated fatty liver disease Proteomics Hepatic steatosis 
MetabolomicsA metabolomic study of urinary changes in type 2 diabetes in human compared to the control group
Type 2 diabetes mellitus is the result of a combination of impaired insulin secretion with reduced insulin sensitivity of target tissues. There are an estimated 150 million affected individuals worldwide, of whom a large proportion remains undiagnosed because of a lack of specific symptoms early in ...
2012-02-14 | MTBLS1 | MetaboLights
ProteomicsProteomics Identification of Opisthorchis viverrini Antigens in Excretory-Secretory matrix
Opisthorchis viverrini (Ov), a Group I biological carcinogen classified by the WHO, is a leading cause of cholangiocarcinoma (CCA) in the Greater Mekong Subregion. Transmission occurs via consumption of raw or undercooked fish harboring Ov metacercariae, which mature into adult Ov worms in the bilia...
ORGANISM(S): Opisthorchiidae 
2026-02-26 | PXD073886 | Pride
Antigens Opisthorchis viverrini (ov) Excretory-secretory maxtrix Proteomics Urine-based diagnostics 
ProteomicsSize matters: Biomolecular compositions of small and large extracellular vesicles in the urine of glioblastoma patients
Glioblastoma is a fatal and devastating primary brain tumour that poses significant challenges to accurate tumour monitoring and patient treatment. Substantial efforts are underway to develop accurate non-invasive liquid biopsy methods that can routinely assess glioblastoma markers in patient body f...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD051553 | Pride
Gliioblastoma Extracellular vesicles Liquid biopsy Urine 
ProteomicsUrine proteomics in IgA nephropathy
we aimed at developing a urinary biomarker-based algorithm that predicts rapid disease progression in IgAN, thus enabling a personalized risk stratification.
ORGANISM(S): Homo sapiens (Human) 
2022-02-15 | PXD020288 | Pride
Ckd Glomerulonephritis : iga Progression Igan Biomarker Urine proteomics 
ProteomicsUrinary polypeptide ETD/CID analysis, part 1
Urine as a biofluid is commonly used in clinical diagnostics, including those performed during pregnancy. Urine is a rich source of polypeptides and protein degradation products, which have been filtered from blood plasma, thus urine has strong potential as a source for novel clinical diagnostics in...
ORGANISM(S): Homo sapiens (Human) 
2016-02-15 | PXD002312 | Pride
Human urine etd cid 
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