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MetabolomicsProfiling the metabolome of uterine fluid for early detection of ovarian cancer

Ovarian cancer (OC) causes high mortality in women because of ineffective biomarkers for early diagnosis. Here, we perform metabolomics analysis on an initial training set of uterine fluid from 96 gynecological patients. A seven-metabolite-marker panel consisting of vanillylmandelic acid, norepin...

2023-03-06 | MTBLS4861 | MetaboLights
MetabolomicsMetabolic Changes of Maternal Uterine Fluid, Uterus, and Plasma during the Peri-implantation Period of Early Pregnancy in Mice
Embryo implantation is a complex process which involves biochemical and physiological interactions between an implantation-competent blastocyst and a receptive uterus. However, the exact biochemical changes of uterine fluid, uterus, and plasma during peri-implantation remain unclear. This study aims...
2020-05-04 | MTBLS627 | MetaboLights
MetabolomicsMetabolomics of uterine fluid of the cow
Not available
ORGANISM(S): Bos taurus 
ST000571 | MetabolomicsWorkbench
ProteomicsProteomic Analysis of Receptive and Non-receptive Endometria-derived Uterine Fluid by LC-MS/MS
The current diagnostic tools used to determine the precise timing of embryo transfer for in vitro fertilization (IVF)-frozen embryo transfer (FET) patients are not non-invasive or accurate. As uterine fluid is collected via a minimally invasive procedure and reflects alterations in the molecular com...
ORGANISM(S): Homo sapiens (Human) 
2025-06-02 | PXD060077 | Pride
Human Endometrial receptivity assessment Biomarker. Embryo implantation Uterine fluid lavage Proteomics 
ProteomicsChicken uterine fluid protein description and quantification
Gallus gallus avian eggshell is a biomineral composed of 95% of calcium carbonate on calcitic form and of 3.5% of an extracellular organic matrix (proteins, polysaccharides and proteoglycans). The calcification process occurred in the lumen of the uterus into the acellular uterine fluid, and is divi...
ORGANISM(S): Gallus gallus (Chicken) 
2014-08-18 | PXD000992 | Pride
Uterine fluid Description Chicken Quantification Lc-ms/ms 
ProteomicsUterine fluid extracellular vesciles proteome in bovine clinical and subclinical endometritis
Uterine fluid (UF) samples were acquired from healthy cows, cows with clinical (CLE) and subclinical endometritis (SE). The extracellular vesicles (EVs) were isolated using size exclusion chromatography-based method. The enrichment of UF-EVs were confirmed with mass-spectrometry of a sample before a...
ORGANISM(S): Bos taurus (Bovine) 
2026-04-27 | PXD044219 | Pride
Uterine fluid Extracellular vesicles Endometritis Bovine Lc/ms-ms 
ProteomicsCharacterization of bovine uterine fluid extracellular vesicles proteomic profiles at follicular and luteal phases of the oestrous cycle
Bovine uterine fluid extracellular vesicles proteomic profile at luteal and follicular phases of the oestrous cycle
ORGANISM(S): Bos taurus (Bovine) 
2023-07-20 | PXD038002 | Pride
Lc-ms/ms Bos taurus 
ProteomicsBovine uterine fluid extracellular vesicle proteome on different timepoints of the oestrous cycle
Healthy cow uterine fluid (UF) was collected from synchronized cattle at day 0, 7 and 16 after ovulation. Extracellular vesicles (EVs) were isolated from UF. UF-EVs from same cattle on different timepoints were subjected to LC-MS/MS. Additionally, one sample before EV purification was subjected to L...
ORGANISM(S): Bos taurus (Bovine) 
2024-01-26 | PXD040201 | Pride
Extracellular vesicles Oestrous cycle timepoints Lc-ms/ms 
ProteomicsIsolation and characterization of equine uterine extracellular vesicles: a comparative methodological study
Extracellular vesicles (EVs) have been identified in the uterine fluid in different species and pointed as key players in the embryo-maternal dialogue, maternal recognition of pregnancy (MRP) and establishment of pregnancy. However, little is known about the uterine EVs in the mare. Therefore, the p...
ORGANISM(S): Equus caballus (Horse) 
2021-09-09 | PXD022264 | Pride
Exosomes Mare Evs protein cargo Uterine fluid Equus caballus Extracellular vesicles Uterus Uterine lavage 
TranscriptomicsTranscription profiling of mouse uterine response 1, 2, 4, 8, 24, 48, and 72 hr after exposure to the reference physiologic estrogen 17 beta-estradiol (E2)
A major challenge in the emerging field of toxicogenomics is to define the relationships between chemically induced changes in gene expression and alterations in conventional toxicologic parameters such as clinical chemistry and histopathology. We have explored these relationships in detail using th...
ORGANISM(S): Mus musculus 
2022-11-20 | E-AFMX-12 | biostudies-arrayexpress
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