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MetabolomicsThe Green Tea Modulates Large Intestinal Microbiome and Exo/Endogenous Metabolome altered through Chronic UVB-exposure (Endogenous assays)
The attenuating effects of green tea supplements (GTS) against the ultraviolet (UV) radiation induced skin damages are distinguished. However, the concomitant effects of GTS on the large intestinal microbiomes and associated metabolomes are largely unclear. Herein, we performed an integrated microbi...
2018-09-14 | MTBLS527 | MetaboLights
MetabolomicsProtective Effect of Ginsenoside Re against UVB-Induced Photodamage in Rats

Background: With the growing prominence of skin photodamage caused by ultraviolet (UV) radiation, the development of efficient and safe natural photoprotectants has become a major research focus. Ginsenoside Re, a rare active component of Panax ginseng, has attracted much attention due to it...

2025-10-16 | MTBLS13149 | MetaboLights
TranscriptomicsThe effects of UVB and the organic osmolyte betaine on rat epidermal keratinocytes in an organotypic culture system
Betaine (trimethylglycine) is a non-toxic, highly water-soluble organic osmolyte widely used in skin care due to its assumed moisturizing and protective properties, but only few studies have addressed its specific effects in skin. Here, the cellular and molecular targets of betaine were analyzed by ...
ORGANISM(S): Rattus norvegicus 
2015-10-26 | E-GEOD-63004 | biostudies-arrayexpress
TranscriptomicsRegulation of human skin pigmentation in situ by repetitive UV exposure - Molecular characterization of responses to UVA, UVB and SSR
To test the hypothesis that different mechanisms and/or factors might be involved in physiological pigmentary responses of the skin to different types of UV, we used whole human genome microarrays and immunohistochemical analyses to characterize human skin in situ to examine how melanocyte-specific ...
ORGANISM(S): Homo sapiens 
2010-08-18 | E-GEOD-21429 | biostudies-arrayexpress
ProteomicsAloin Protects Against UVB-Induced Apoptosis
This study comprehensively investigates the photoprotective effects of aloin against UVB-induced damage in HaCaT cells, elucidating its antioxidant capacity and its role in preventing cellular apoptosis. The proteomic effect of 50 μg/mL aloin on HaCaT cell damage induced by UVB was evaluated through...
ORGANISM(S): Homo sapiens (Human) 
2025-08-04 | PXD060808 | Pride
Hacat cells Aloin Uvb-induced apoptosis 
TranscriptomicsBmal1 controls circadian cell proliferation and susceptibility to UVB-induced DNA damage in the epidermis
This SuperSeries is composed of the following subset Series: GSE38622: Bmal1 controls circadian cell proliferation and susceptibility to UVB-induced DNA damage in the epidermis [telogen]. GSE38623: Bmal1 controls circadian cell proliferation and susceptibility to UVB-induced DNA damage in the epider...
ORGANISM(S): Mus musculus 
2012-08-01 | E-GEOD-38625 | biostudies-arrayexpress
GenomicsUVB induces a major genome-wide rearrangement of RNA polymerase II at transcribed human genes
Abstract Background: Faithful transcription of DNA is constantly threatened by different endogenous and environmental genotoxic effects. Transcription coupled repair has been described to quickly remove DNA lesions from the transcribed strand of active genes, permitting rapid resumption of blocked ...
ORGANISM(S): Homo sapiens 
2014-07-25 | E-GEOD-52789 | biostudies-arrayexpress
ProteomicsTaxifolin protects HaCaT keratinocytes from UVB damage
The photoprotective efficacy and underlying mechanisms of taxifolin against UVB-induced injury were evaluated in human immortalized keratinocytes (HaCaT).
ORGANISM(S): Homo sapiens (Human) 
2026-04-06 | PXD073279 | Pride
Taxifolin Proteome Hacat 
TranscriptomicsBmal1 controls circadian cell proliferation and susceptibility to UVB-induced DNA damage in the epidermis [telogen].
While several physiological skin parameters vary in a circadian manner, the identity of genes participating in chronobiology of skin remains unknown, leading us to define the circadian transcriptome of mouse skin at two different stages of the hair cycle, telogen and anagen. The circadian transcrip...
ORGANISM(S): Mus musculus 
2012-08-01 | E-GEOD-38622 | biostudies-arrayexpress
TranscriptomicsBmal1 controls circadian cell proliferation and susceptibility to UVB-induced DNA damage in the epidermis [Anagen]
While several physiological skin parameters vary in a circadian manner, the identity of genes participating in chronobiology of skin remains unknown, leading us to define the circadian transcriptome of mouse skin at two different stages of the hair cycle, telogen and anagen. The circadian transcrip...
ORGANISM(S): Mus musculus 
2012-08-01 | E-GEOD-38623 | biostudies-arrayexpress
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