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Previously we reported that a recombinant vaccinia virus (VACV) carrying a light-emitting fusion gene enters, replicates in, and reveals the locations of tumors in mice. A new recombinant VACV, GLV-1h68, as a simultaneous diagnostic and therapeutic agent, was constructed by inserting three expressio...
ORGANISM(S): Mus musculus 
We report the analysis of tumor infiltrating lymphocytes from a mouse melanoma model that were treated with PBS, CTRL virus or leptin expressinb vaccina oncolytic virus
ORGANISM(S): Mus musculus 
2019-09-03 | GSE133699 | GEO
Single cell RNA sequencing CD45+ TIL samples from melanoma mouse model treated with leptin expressing vaccinia virus.
Previously we reported that a recombinant vaccinia virus (VACV) carrying a light-emitting fusion gene enters, replicates in, and reveals the locations of tumors in mice. A new recombinant VACV, GLV-1h68, as a simultaneous diagnostic and therapeutic agent, was constructed by inserting three expressio...
ORGANISM(S): Mus musculus 
2007-12-26 | GSE8513 | GEO
tRNAs are widely recognized for their role in translation. Here we describe a previously unidentified function of tRNA as an assembly chaperone. During poxviral infection tRNAGln/Arg lacking the anticodon mcm5s2U modification is specifically recruited from the cellular tRNA pool to a multi-subunit p...
ORGANISM(S): Homo sapiens (Human) Vaccinia virus GLV-1h68 
2025-11-24 | PXD057359 | Pride
Eradication of Solid Human Tumors in Nude Mice with an Intravenously Injected Light-Emitting Oncolytic Vaccinia Virus
Vaccinia virus evolution reveals adaptations to evade host viral nucleic acid sensing
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