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MetabolomicsMetabolites interact with microorganisms and vaccines
we engineered a β-glucan (Dex)-stabilized mulberry leaf lipid-based nanovaccine (DPML@OVA-CpG) that protected vaccine components during GI transit and facilitated their specific delivery to the GALTs. Following oral administration, the DPML@OVA-CpG underwent M cell-mediated transcytosis in the small...
2026-08-25 | MTBLS15453 | MetaboLights
TranscriptomicsPlasmablast response to influenza vaccines
To study the plasmablast response to influenza vaccines We want to test and see that LAIV, TIV and ID TIV induced different plasmablast response We take peripheral plasmablast and test its response to influenza vaccines at day 7 after vaccination. This array data set is for day 0 (before vaccines)
ORGANISM(S): Homo sapiens 
2016-07-01 | E-GEOD-62110 | biostudies-arrayexpress
UnknownEquity-Informative Economic Evaluations of Vaccines: A Systematic Literature Review.
Not available
S-EPMC10057152 | biostudies-literature
ProteomicsComparative analysis of ChAdOx1 nCoV-19 and Ad26.COV2.S SARS-CoV-2 vector vaccines
Vector-based SARS-CoV-2 vaccines such as AstraZeneca's ChAdOx1 nCoV-19 have been associated with vaccine-induced thrombosis (TTS/VITT). We studied ChAdOx1 nCov-19 (AstraZeneca) and Ad26.COV2.S (Johnson & Johnson) and compared the vaccines using proteomics with mass spectrometric measurements. We cou...
ORGANISM(S): Homo sapiens (Human) 
2023-05-04 | PXD027344 | Pride
Ad26.cov2.s Sars-cov-2 Vector vaccines Chadox1 
TranscriptomicsGenome-wide profiling of whole blood from healthy adult volunteers before and after receiving non-live vaccines including seasonal influenza or pneumococcal vaccine or placebo (saline) injections.
The objective of this study is to: 1) Characterize the immune responsiveness to administration of non-live vaccines in three cohorts of healthy adult subjects through the analysis of blood leukocytes transcriptional profiles. 2) Validate whole blood transcriptional profiles generated from standard 3...
ORGANISM(S): Homo sapiens 
2013-04-19 | E-GEOD-30101 | biostudies-arrayexpress
TranscriptomicsGenome-wide profiling of whole blood from healthy adult volunteers before and after receiving non-live vaccines including seasonal influenza or pneumococcal vaccine or placebo (saline) injections II
The objective of this study is to: 1) Characterize the immune responsiveness to administration of non-live vaccines in three cohorts of healthy adult subjects through the analysis of blood leukocytes transcriptional profiles. 2) Validate whole blood transcriptional profiles generated from standard 3...
ORGANISM(S): Homo sapiens 
2013-07-10 | E-GEOD-48762 | biostudies-arrayexpress
TranscriptomicsGenome-wide profiling of whole blood from healthy adult volunteers before and after receiving non-live vaccines including seasonal influenza or pneumococcal vaccine or placebo (saline) injections I
The objective of this study is to: 1) Characterize the cellular origin of transciptional signatures observed on day 1 after vaccination with 2009/10 seasonal influenza and pneumococcal vaccine discovered by transcriptional profiling of whole blood samples in data set “WholeBlood_SysVax”. 2) Discover...
ORGANISM(S): Homo sapiens 
2013-07-10 | E-GEOD-30059 | biostudies-arrayexpress
ProteomicsProteomics of Bordetella pertussis whole-cell and acellular vaccines
Bordetella pertussis is the etiological agent of whooping cough, a bacterial infection of especially children, which may be fatal without treatment. In frame of studies to investigate putative effects of vaccination on host-pathogen interaction and clonal distribution of strains, in addition to Cory...
ORGANISM(S): Corynebacterium diphtheriae NCTC 13129 Clostridium tetani E88 Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251) 
2019-05-14 | PXD013804 | Pride
Whooping cough Mass spectrometry Bordetella Dtp vaccine Vaccination Pertussis Lc-ms/ms 
MetabolomicsPharmacological Targeting of ALDH1a2 in Dendritic Cells Enhances Antigen Presentation, T Cell Activation and Anti-tumor immunity
Dendritic cell (DC) vaccines have been proposed as cancer immunotherapies due to their role as crucial antigen-presenting cells that regulate T cell functions. Despite considerable efforts to optimize ex vivo priming of DCs, DC vaccines have rarely been successful, suggesting the presence of unknown...
2025-11-03 | MTBLS10389 | MetaboLights
ProteomicsTopological N-glycosylation and site-specific N-glycan sulfation of influenza proteins in the highly expressed H1N1 candidate vaccines
The outbreak of a pandemic influenza H1N1 in 2009 required the rapid generation of high-yielding vaccines against the A/California/7/2009 virus, which were achieved by either addition or deletion of a glycosylation site in the influenza proteins hemagglutinin and neuraminidase. In this report, we ha...
ORGANISM(S): Homo sapiens (Human) 
2018-11-21 | PXD007037 | Pride
Influenza h1n1 Lc ms/ms 
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