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ProteomicsMapping the binding site of VAR2CSA to chondroitin sulfate A
The FPOP was performed in order to map the binding site of chondroitin sulfate A to VAr2CSA from Plasmodium.
ORGANISM(S): Plasmodium falciparum FcB1/Columbia 
2021-04-09 | PXD024154 | Pride
Chondoitin sulfate a Hrpf Var2csa Fpop 
ProteomicsAP-MS with VAR2CSA and oncofetal chondroitin sulfate antibodies
Tumors display oncofetal chondroitin sulfate (ofCS) glycosaminoglycans that support disease progression and dissemination. ofCS can be detected by the the Plasmodium falciparum derived VAR2CSA protein but the development of recombinant VAR2CSA as a clinical tool has proven challenging. Here, we perf...
ORGANISM(S): Homo sapiens (Human) 
2024-08-31 | PXD044455 | Pride
Ap-ms Chondroitin sulfate Lc-ms Var2csa Cancer 
ProteomicsMolecular architecture and domain arrangement of the placental malaria protein VAR2CSA suggests a model for carbohydrate binding
VAR2CSA is the placental-malaria specific member of the antigenically variant Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) family. It is expressed on the surface of Plasmodium falciparum infected host red blood cells and binds to specific chondroitin-4-sulfate chains of the placenta...
ORGANISM(S): Homo sapiens (Human) 
2020-12-02 | PXD021873 | Pride
Lc-msms 
UnknownStructural basis for placental malaria mediated by Plasmodium falciparum VAR2CSA.
Not available
S-EPMC7914210 | biostudies-literature
UnknownStructural insight into epitopes in the pregnancy-associated malaria protein VAR2CSA.
Not available
S-EPMC2242842 | biostudies-literature
Genomics
Plasmodium falciparum var2csa ID1-DBL2X PacBio deep sequencing
PRJNA398389 | ENA
UnknownUtilizing nanobody technology to target non-immunodominant domains of VAR2CSA.
Not available
S-EPMC3897377 | biostudies-literature
UnknownOptimizing expression of the pregnancy malaria vaccine candidate, VAR2CSA in Pichia pastoris.
Not available
S-EPMC2714522 | biostudies-literature
UnknownA single full-length VAR2CSA ectodomain variant purifies broadly neutralizing antibodies against placental malaria isolates.
Not available
S-EPMC8959597 | biostudies-literature
UnknownPlasmodium falciparum genetic variation of var2csa in the Democratic Republic of the Congo.
Not available
S-EPMC5782373 | biostudies-literature
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