Sort   by:  
 Page size 
MetabolomicsMulti-omics analysis reveals microbiota-metabolite crosstalk in MASLD pathogenesis in a non-obese murine model

The rising global prevalence of metabolic dysfunction-associated steatotic liver disease (MASLD), including its severe form metabolic dysfunction-associated steatohepatitis (MASH), underscores the urgency to elucidate its pathophysiology. To investigate key metabolic interactions central to MASLD...

2026-03-13 | MTBLS14048 | MetaboLights
ProteomicsIdentification of spidroin proteins in the silk glands of Nephila clavipes spiders
Glands were frozen at -80 ºC immediately after being retrieved and stored under this condition until initiating the proteomics analysis protocol. Glands were washed with cold PBS and immersed in 120 l of homogenization buffer (50 mM Tris-HCl, pH 6.8, 10 mM DTT, 4% (w/v) SDS). Glands were boiled for ...
ORGANISM(S): Trichonephila clavipes 
2022-12-07 | PXD023141 | Pride
Spider silk  proteomics  liquid chromatography-tandem mass spectrometry  silk gut 
UnknownA data base of contributions of major oceanic and terrestrial moisture sources on continental daily extreme precipitation.
Not available
S-EPMC7896140 | biostudies-literature
MetabolomicsAntibiotics create a shift from mutualism to competition in human gut communities with a longer-lasting impact on fungi than bacteria

Background

Antibiotic treatment has a well-established detrimental effect on the gut bacterial composition, but effects on the fungal community are less clear. Bacteria in the lumen of the gastrointestinal tract may limit fungal colonization and invasion. Antibiotic drugs t...

2020-09-28 | MTBLS1846 | MetaboLights
ProteomicsProteome profiling of cultivated Echerichia coli isolates from Crohn's disease patients
One of the dysbioses often observed in CD patients is an increased abundance of Escherichia coli (10-100 fold compared to healthy individuals) [Gevers et al., 2014]. E. coli isolates collected from CD and healthy patients were cultivated on LB medium at aerobic conditions up to medium log phase and...
ORGANISM(S): Escherichia coli 
2019-08-15 | PXD010920 | Pride
Crohn's disease Hplc-ms/ms Proteome E. coli 
TranscriptomicsTranscription profiling of rat astrocytes in culture and from human optic nerve to identify acutely expressed genes during CNS injury and their expression in cultured astrocytes
A robust set of CNS transcript changes was defined by comparing microarray data that describe the injury response of the rat retina [Vazquez-Chona et al., IOVS 2004; GSE1001], brain [Matzilevich et al., J Neurosci Res 2002; GSE1911], and spinal cord [Di Giovanni et al., Ann Neurol 2003; GDS63]. We d...
ORGANISM(S): Homo sapiens 
2008-06-11 | E-GEOD-1928 | biostudies-arrayexpress
TranscriptomicsCharacterization of the starvation response in the Arabidopsis dcl1-9 mutant
The SnRK1 protein kinase, the plant ortholog of mammalian AMPK and yeast Snf1, is activated by the energy depletion caused by adverse environmental conditions. Upon activation, SnRK1 triggers extensive transcriptional changes to restore homeostasis and promote stress tolerance and survival partly th...
ORGANISM(S): Arabidopsis thaliana 
2013-07-15 | E-GEOD-46713 | biostudies-arrayexpress
UnknownGenomic loci modulating the retinal transcriptome in wound healing.
Not available
S-EPMC2759132 | biostudies-literature
MetabolomicsCharacterization of Cabernet Sauvignon Wines by Untargeted HS-SPME GC-QTOF-MS
Untargeted metabolomics approaches are emerging as powerful tools for the quality evaluation and authenticity of food and beverages and have been applied to wine science. However, most fail to report the method validation, quality assurance and/or quality control applied, as well as the assessment t...
2022-04-29 | MTBLS1391 | MetaboLights
TranscriptomicsEnvironment-responsive transcription factors bind proto-silencer elements and regulate subtelomeric silencing
Subtelomeric chromatin is subject to evolutionarily conserved complex epigenetic regulation and is implicated in numerous aspects of cellular function including formation of heterochromatin, regulation of different stress response pathways, and control of lifespan. Subtelomeric DNA is characterized...
ORGANISM(S): Saccharomyces cerevisiae 
2011-05-02 | E-GEOD-21852 | biostudies-arrayexpress
Sort   by:  
 Page size