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ProteomicsBlood exposure induces global changes in gene expression and protein secretion of B. pertussis
This project was focused on transcriptome and secretome of pathogenic bacteria B. pertussis, which were cultivated on solid plates (charcoal agar) with/without blood and subsequently sub-cultured in liquid media. As a standard, Bordetella spp. strain are grown on agar plates supplemented with blood....
ORGANISM(S): Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251) 
2021-09-09 | PXD022760 | Pride
Blood Lfq ms Bordetella pertussis Virulence factors 
ProteomicsBtcB (BP2265) is a T3SS chaperone of the CesT family in Bordetella pertussis
Bordetella pertussis is a Gram-negative, strictly human respiratory pathogen and the causative agent of whooping cough (pertussis). Similar to other Gram-negative pathogens, B. pertussis produces a functional type III secretion system, but its role in pathogenesis of B. pertussis is enigmatic and ha...
ORGANISM(S): Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251) Bordetella pertussis B1917 
2024-01-26 | PXD044487 | Pride
Lc-msms T3ss Bordetella pertussis Rna-seq 
ProteomicsComparative integrated omics analysis of the Hfq regulon in Bordetella pertussis
This study represents the first attempt to characterize the RNA chaperone Hfq regulon in bacterial pathogen using an integrative omics approach. Gene expression profiles were analyzed by RNA-seq and protein amounts in cell-associated and cell-free fractions were determined by LC-MS/MS technique. Com...
ORGANISM(S): Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251) 
2019-07-02 | PXD013953 | Pride
Hfq regulon Lfq ms Bordetella pertussis 
ProteomicsCOMPARATIVE OMICS ANALYSIS OF HISTORICAL AND RECENT ISOLATES OF BORDETELLA PERTUSSIS
Despite high vaccination coverage, pertussis is on the rise in many countries including Czech Republic. To better understand B. pertussis resurgence we compared the changes in genome structures between Czech vaccine and circulating strains and subsequently, we determined how these changes translated...
ORGANISM(S): Bordetella pertussis Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251) 
2021-09-08 | PXD015184 | Pride
Adaptation Is elements Genomic rearrangement Omics analysis Bordetella pertussis 
ProteomicsGlobal analysis of the Hfq-mediated RNA interactome discovers a MicA homolog of Bordetella pertussis
Bordetella pertussis is a Gram-negative, strictly human re-emerging respiratory pathogen and the causative agent of whooping cough. The requirement of the RNA chaperone Hfq for the virulence of B. pertussis suggests that Hfq-dependent small regulatory RNAs (sRNAs) are involved in the virulence of th...
ORGANISM(S): Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251) 
2025-07-14 | PXD063711 | Pride
Omics analysis Srna Bordetella pertussis Ril-seq Outer membrane Biofilm 
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