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UnknownOestrogen Non-Genomic Signalling is Activated in Tamoxifen-Resistant Breast Cancer.
Not available
S-EPMC6600329 | biostudies-literature
UnknownINMUNOCAT study: The impact of molecular diagnosis on immunotherapy prescription in pollen polysensitized patients from Catalonia.
Not available
S-EPMC10154984 | biostudies-literature
ProteomicsAcidosis attenuates the hypoxic stabilization of HIF-1α by activating its lysosomal degradation
The adaptive responses to oxygen depletion orchestrated by hypoxia-inducible factors (HIFs) produce profound effects on multiple pathways. A canonical metabolic response is enhanced fermentation, but this can generate an unfavorably acidic environment under poor capillary perfusion. It is unclear ho...
ORGANISM(S): Homo sapiens (Human) 
2025-06-30 | PXD062474 | Pride
Acidosis Colorectal cancer Hypoxia inducible factor Hypoxia Tumour microenvironment Sw1222 
UnknownAn Oral Salmonella-Based Vaccine Inhibits Liver Metastases by Promoting Tumor-Specific T-Cell-Mediated Immunity in Celiac and Portal Lymph Nodes: A Preclinical Study.
Not available
S-EPMC4771756 | biostudies-literature
ProteomicsAn unconventional integrin promotes human immunityAn unconventional integrin promotes human immunity
Cancer remains one of the leading causes of mortality worldwide, with increasing public health interest towards immunological-based approach in disease treatments. Enrichment of certain cell population, namely the CD103+ tissue-resident memory T (Trm) cells has been associated with better clinical p...
ORGANISM(S): Homo sapiens (Human) 
2024-07-30 | PXD045989 | Pride
Human Cancer immunology Interactomics 
Transcriptomicsidentification of miRNA differential expression patterns in a new model of acquired letrozole resistance
Since differential miRNA expression patterns associated with acquired AI resistance have been poorly investigated, the aim of this study was to delineate the deregulation of miRNA expression associated with letrozole response failure in a new model of letrozole resistance. For this purpose, we gener...
ORGANISM(S): Homo sapiens 
2013-01-30 | E-GEOD-43766 | biostudies-arrayexpress
ProteomicsViral control by a unique cytotoxic SARS-CoV-2 spike protein-specific CD4+ T cell population
Little is known of the role of cytotoxic CD4+ T-cells (CTLs) in the control of human viral replication. Here, we investigate CD4+ T-cell responses to three immunodominant SARS-CoV-2 epitopes identified in our study cohort, and evaluate cytotoxic activity and antiviral cytokine production in response...
ORGANISM(S): Severe acute respiratory syndrome coronavirus 2 Homo sapiens (Human) 
2025-08-15 | PXD042469 | Pride
Human Epitotpes Sars-cov-2 Cd4+ tcells Lc-ms/ns 
MetabolomicsDeficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease
Non-alcoholic fatty liver is the most common liver disease worldwide. Here, we show that the mitochondrial protein mitofusin 2 (Mfn2) protects against liver disease. Reduced Mfn2 expression was detected in liver biopsies from patients with non-alcoholic steatohepatitis (NASH). Moreover, reduced Mfn2...
2018-01-25 | MTBLS600 | MetaboLights
UnknownDifferential Profiles of Gut Microbiota-Derived Metabolites of Bile Acids and Propionate as Potential Predictors of Depressive Disorder in Women with Morbid Obesity at High Risk of Metabolic Dysfunction-Associated Steatotic Liver Disease-A Pilot Study.
Not available
S-EPMC12110740 | biostudies-literature
UnknownDetection of known and novel ALK fusion transcripts in lung cancer patients using next-generation sequencing approaches.
Not available
S-EPMC5624911 | biostudies-literature
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